Target Name: FNDC5
NCBI ID: G252995
Review Report on FNDC5 Target / Biomarker Content of Review Report on FNDC5 Target / Biomarker
FNDC5
Other Name(s): fibronectin type III repeat-containing protein 2 | FRCP2 | irisin | Fibronectin type III domain-containing protein 5 (isoform 1) | fibronectin type III domain containing 5 | FNDC5_HUMAN | Fibronectin type III domain containing 5, transcript variant 1 | Fibronectin type III repeat-containing protein 2 | Fibronectin type III domain-containing protein 5 | FNDC5 variant 1 | Irisin

FNDC5: A Potential Drug Target and Biomarker

Fibronectin (FN) is a protein that plays a critical role in cell-cell adhesion, tissue repair, and regeneration. FN is composed of multiple repeating units, including type III repeat, which is the most important functional unit in the FN structure. Type III repeat is a repeating unit composed of 256 amino acids, and its presence gives FN a high degree of specific binding ability. FNDC5 is a protein that plays an important role in humans and has potential therapeutic effects on a variety of diseases. This article will introduce the basic information, function, possibility of being a drug target and application prospects of FNDC5 as a biomarker.

Basic information about FNDC5

FNDC5 is a 120kDa polypeptide composed of two subunits, each containing 40 amino acids. The N-terminus of FNDC5 contains an 伪-helix, the middle end contains a 尾-sheet, and a C-tail. The repeating unit of FNDC5 consists of two 伪-helices flanked by 尾-sheets. The structure of this repeating unit gives FNDC5 a highly specific binding ability and interacts with other proteins.

Functions of FNDC5

FNDC5 plays an important role in a variety of physiological processes. During cell division, FNDC5 helps maintain the integrity of the cell membrane and participates in the regulation of cell division. FNDC5 is also involved in the synthesis and secretion of extracellular matrix and plays an important role in wound healing and tissue regeneration. In addition, FNDC5 is also involved in cell signaling and regulates cell proliferation and differentiation.

FNDC5 as a drug target

FNDC5 has high potential as a drug target. First, FNDC5 has unique biological properties that make it an attractive drug target. Secondly, FNDC5 plays an important role in a variety of pathological processes, which provides opportunities for the development of drugs to treat multiple diseases. Finally, the drug target status of FNDC5 has been confirmed, which provides an important theoretical basis for drug development.

The application prospects of FNDC5 as a biomarker

FNDC5 can also be used as a biomarker for disease diagnosis and treatment. For example, FNDC5 could be used to treat cirrhosis because it can be used to detect the extent of cirrhosis and evaluate the effectiveness of treatments for cirrhosis. FNDC5 could also be used to treat cancer, as it can be used to detect tumor aggressiveness and assess tumor response to immunotherapy. In addition, FNDC5 can also be used to detect other diseases, such as diabetes, obesity, neurodegenerative diseases, etc.

in conclusion

FNDC5 is a protein with multiple biological properties. It plays an important role in cell division, extracellular matrix synthesis, cell signaling, wound healing and tissue regeneration. FNDC5 also has unique biological properties that make it an attractive drug target. In addition, FNDC5 can also be used as a biomarker for disease diagnosis and treatment. Therefore, FNDC5 is a promising drug target and has high application potential.

Protein Name: Fibronectin Type III Domain Containing 5

Functions: Contrary to mouse, may not be involved in the beneficial effects of muscular exercise, nor in the induction of browning of human white adipose tissue

The "FNDC5 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about FNDC5 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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