OR4S1: A GPCR Molecule Implicated in Olfactory Perception and Neurotransmission
OR4S1: A GPCR Molecule Implicated in Olfactory Perception and Neurotransmission
OR4S1 (Olfactory Receptor Family 4 Subfamily S Member 1) is a protein that is expressed in the olfactory epithelial cells of the nose. It is a member of the Olfactory Receptor Family 4, which is a family of olfactory receptor proteins, and is responsible for mediating the sense of smell. OR4S1 is a G protein-coupled receptor (GPCR), which is a transmembrane protein that is involved in a variety of cellular processes, including sensory perception and neurotransmission.
OR4S1 is expressed in the olfactory epithelial cells of the nose, which are the specialized cells that line the nasal passages and are responsible for transmitting the sense of smell to the brain. These cells are located in the nasal cavity, and they project out of the nasal passages into the nasal passages, where they are able to recognize and respond to the scents that are present in the air. OR4S1 is one of the proteins that is involved in this process.
OR4S1 is a GPCR that is characterized by its four transmembrane domains. These domains give OR4S1 its unique structure and its ability to interact with a variety of different molecules. The first domain is a catalytic domain, which is responsible for the catalytic activity of OR4S1. This domain is composed of a Rossmann-fold, which is a specific type of hydrogen bonding that allows OR4S1 to interact with other molecules in a specific way.
The second domain is a transmembrane domain, which is responsible for the structural integrity of the OR4S1 protein. This domain is composed of a series of transmembrane伪 helices, which are able to form a continuous transmembrane region that spans the entire width of the cell membrane.
The third domain is a variable region, which is responsible for the diversity of OR4S1. This region is composed of several variable loops, which are able to alter the conformation of the OR4S1 protein and allow it to interact with a variety of different molecules.
The fourth domain is a C-terminal domain, which is responsible for the stability and half-life of OR4S1. This domain is composed of a series of amino acids that are able to form a C-terminal tail that can be involved in protein-protein interactions and other cellular processes.
OR4S1 is a GPCR that is involved in a variety of different cellular processes, including sensory perception and neurotransmission. stress resistance and learning. OR4S1 is also able to interact with other GPCRs, including OR4S2 and OR4S3, which are also involved in the sense of smell.
OR4S1 is also a potential drug target, due to its involvement in sensory perception and neurotransmission. Methods such as live cell imaging, RNA interference, and mass spectrometry have been used to study the effects of drugs on OR4S1 expression and function. These studies have shown that drugs that are able to block the activity of OR4S1 can have a variety of different effects on sensory perception and neurotransmission.
In addition to its potential as a drug target, OR4S1 is also a valuable biomarker for the diagnosis and monitoring of various neurological and psychiatric disorders, such as Alzheimer's disease, Parkinson's disease, and schizophrenia. Studies have shown that the levels of OR4S1 in the olfactory epithelial cells of individuals with these disorders are significantly decreased compared to those of individuals without the disorders. This suggests that OR4S1 may be a useful biomarker for the diagnosis and monitoring of these disorders.
In conclusion, OR4S1 (Olfactory Receptor Family 4 Subfamily S Member 1) is a protein that is expressed in the olfactory epithelial cells of the nose that is responsible for mediating the sense of smell. It is a GPCR and is involved in a variety of different cellular processes, including sensory perception and neurotransmission. OR4S1 is also a potential drug target and a valuable biomarker for the diagnosis and monitoring of various neurological and psychiatric disorders. Further research is needed to fully understand the role of OR4S1 in these processes and its potential as a therapeutic target.
Protein Name: Olfactory Receptor Family 4 Subfamily S Member 1
Functions: Odorant receptor
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More Common Targets
OR4S2 | OR4T1P | OR4V1P | OR4X1 | OR4X2 | OR51A1P | OR51A2 | OR51A3P | OR51A4 | OR51A6P | OR51A7 | OR51B2 | OR51B4 | OR51B5 | OR51B6 | OR51C1P | OR51D1 | OR51E1 | OR51E2 | OR51F1 | OR51F2 | OR51G1 | OR51G2 | OR51H1 | OR51I1 | OR51I2 | OR51J1 | OR51L1 | OR51M1 | OR51Q1 | OR51S1 | OR51T1 | OR51V1 | OR52A1 | OR52A4P | OR52A5 | OR52B2 | OR52B4 | OR52B6 | OR52D1 | OR52E1 | OR52E2 | OR52E4 | OR52E5 | OR52E6 | OR52E8 | OR52H1 | OR52I1 | OR52I2 | OR52J3 | OR52K1 | OR52K2 | OR52K3P | OR52L1 | OR52M1 | OR52N1 | OR52N4 | OR52N5 | OR52R1 | OR52W1 | OR52Z1P | OR56A1 | OR56A3 | OR56A4 | OR56A5 | OR56B1 | OR56B4 | OR5A1 | OR5A2 | OR5AC1 | OR5AC2 | OR5AK2 | OR5AK4P | OR5AN1 | OR5AP2 | OR5AR1 | OR5AS1 | OR5AU1 | OR5B12 | OR5B17 | OR5B2 | OR5B21 | OR5B3 | OR5BA1P | OR5C1 | OR5D13 | OR5D14 | OR5D16 | OR5D17P | OR5D18 | OR5E1P | OR5F1 | OR5H1 | OR5H14 | OR5H15 | OR5H2 | OR5H4P | OR5H6 | OR5I1 | OR5K1
