OR5AP2: A Protein Linked To Multiple Disorders and Potential Drug Target

OR5AP2: A Protein Linked To Multiple Disorders and Potential Drug Target

Olfactory receptor 5AP2 (OR5AP2) is a protein that is expressed in the sweat glands and is responsible for mediating the sense of smell. Mutations in the OR5AP2 gene have been linked to a range of disorders, including chronic rhinitis, a common respiratory condition that causes stuffiness, itching, and difficulty breathing through the nose. In addition, OR5AP2 has also been shown to play a role in cancer, and research is ongoing to determine its potential as a drug target or biomarker.

The OR5AP2 gene is located on chromosome 7 and encodes a protein that is composed of 254 amino acids. The protein has a molecular weight of 31.4 kDa and a calculated pI of 2.8. OR5AP2 is expressed in the sweat glands, hair, and nail, and is responsible for mediating the sense of smell. The OR5AP2 protein is a member of the superfamily of G protein-coupled receptors (GPCRs), which are a family of transmembrane proteins that play a role in sensory perception and other physiological processes.

Mutations in the OR5AP2 gene have been linked to a range of disorders, including chronic rhinitis, a common respiratory condition that causes stuffiness, itching, and difficulty breathing through the nose. Chronic rhinitis is a condition that is characterized by a persistent stuffiness, nosebleeds, and sneezing. In addition, OR5AP2 mutations have also been linked to other disorders, including dry eye syndrome, a condition that causes dryness and itching of the eyes, and neurodegenerative diseases, including Alzheimer's disease and Parkinson's disease.

In addition to its role in sensory perception, OR5AP2 has also been shown to play a role in cancer.Studies have shown that OR5AP2 is a potential drug target for cancer, and that inhibiting its activity may be a promising strategy for the treatment of certain types of cancer. In addition, research is ongoing to determine the potential benefits and risks of targeting OR5AP2 as a cancer biomarker.

The OR5AP2 gene has also been the subject of research into its potential as a drug target. Studies have shown that OR5AP2 is a strong candidate for inhibition as a therapeutic agent for a range of conditions, including respiratory diseases, neurodegenerative diseases, and cancer. In addition, research is ongoing to determine the most effective and efficient way to target OR5AP2 as a drug.

In conclusion, Olfactory receptor 5AP2 is a protein that is expressed in the sweat glands and is responsible for mediating the sense of smell. Mutations in the OR5AP2 gene have been linked to a range of disorders, including chronic rhinitis and neurodegenerative diseases. In addition, OR5AP2 has also been shown to play a role in cancer, and research is ongoing to determine its potential as a drug target or biomarker. Further research is needed to fully understand the role of OR5AP2 in these processes and to determine the most effective way to target it as a therapeutic agent.

Protein Name: Olfactory Receptor Family 5 Subfamily AP Member 2

Functions: Odorant receptor

The "OR5AP2 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about OR5AP2 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
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•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets

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