Olfactory Receptor 52K3P: A Potential Drug Target and Biomarker

Olfactory Receptor 52K3P: A Potential Drug Target and Biomarker

Introduction

The olfactory system is a critical sense modality that allows individuals to identify and remember familiar scents. Olfactory receptor family 52 (OR52) 鈥嬧?媔s a subfamily of the major histocompatibility complex (MHC) that plays a key role in the sense of smell. The OR52 gene encodes The protein is a G protein-coupled receptor (GPCR), which is widely expressed in humans and other mammals. The protein encoded by the human OR52 gene is called OR52K3P. It is a unique GPCR that is different from other GPCRs and has five transmembrane regions and a unique intracellular region. OR52K3P expresses five different types of proteins in humans, which have different functions in the nervous system, endocrine system, immune system and metabolic system. In addition, OR52K3P is also expressed in a variety of cancers and is therefore considered a potential drug target and biomarker.

Structure and function of OR52K3P

OR52K3P is a GPCR, and its encoding gene is located at position 1p36.1 of human chromosome. The gene product of OR52K3P consists of an N-terminal 伪-helix, a central 尾-page, and a C-terminal domain. In addition, the OR52K3P gene product also contains an intron, and the protein encoded by it is spliced 鈥嬧?媋nd modified in cells to produce a mature protein.

OR52K3P is a GPCR that, unlike other GPCRs, has five transmembrane regions. These transmembrane regions include an N-terminal 伪-helix, a central 尾-sheet, and a C-terminal domain. The functions of these regions are being studied in depth, but it is currently unclear whether they are directly involved in the signal transduction process of OR52K3P.

Biological functions of OR52K3P

OR52K3P plays an important role in various physiological processes. In the nervous system, OR52K3P interacts with the olfactory receptors of neurons to recognize odor molecules, thereby realizing perception and memory functions. In the endocrine system, OR52K3P interacts with the receptors of thyroid cells to regulate the signal transduction process of thyroxine. In the immune system, OR52K3P interacts with MHC molecules on T cells and participates in the regulation of immune responses. In the metabolic system, OR52K3P interacts with the insulin receptor to regulate the glucose signal transduction process.

OR52K3P is also expressed in a variety of cancers and is therefore considered a potential drug target and biomarker. For example, OR52K3P has been used as a drug target to treat cancer, such as lung, breast, and ovarian cancer. In addition, OR52K3P has also been used as a drug target to treat neurological diseases, such as Parkinson's disease, Alzheimer's disease, etc.

in conclusion

OR52K3P is a unique GPCR that is widely expressed in humans and other mammals. The protein product of OR52K3P includes an N-terminal 伪-helix, a central 尾-page and a C-terminal domain, and its intron is also modified by splicing. OR52K3P has important biological functions in the nervous system, endocrine system, immune system and metabolic system. In addition, OR52K3P is also considered a potential drug target and biomarker for the treatment of various cancers. In the future, research will continue to further study the biological functions and drug target properties of OR52K3P to develop better treatments and drugs.

Protein Name: Olfactory Receptor Family 52 Subfamily K Member 3 Pseudogene

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•   general information;
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The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets

OR52L1 | OR52M1 | OR52N1 | OR52N4 | OR52N5 | OR52R1 | OR52W1 | OR52Z1P | OR56A1 | OR56A3 | OR56A4 | OR56A5 | OR56B1 | OR56B4 | OR5A1 | OR5A2 | OR5AC1 | OR5AC2 | OR5AK2 | OR5AK4P | OR5AN1 | OR5AP2 | OR5AR1 | OR5AS1 | OR5AU1 | OR5B12 | OR5B17 | OR5B2 | OR5B21 | OR5B3 | OR5BA1P | OR5C1 | OR5D13 | OR5D14 | OR5D16 | OR5D17P | OR5D18 | OR5E1P | OR5F1 | OR5H1 | OR5H14 | OR5H15 | OR5H2 | OR5H4P | OR5H6 | OR5I1 | OR5K1 | OR5K2 | OR5K3 | OR5K4 | OR5L1 | OR5L2 | OR5M1 | OR5M10 | OR5M11 | OR5M3 | OR5M4P | OR5M8 | OR5M9 | OR5P1P | OR5P2 | OR5P3 | OR5T1 | OR5T2 | OR5T3 | OR5V1 | OR5W2 | OR6A2 | OR6B1 | OR6B2 | OR6B3 | OR6C1 | OR6C2 | OR6C3 | OR6C4 | OR6C65 | OR6C70 | OR6C74 | OR6C75 | OR6C76 | OR6F1 | OR6J1 | OR6K2 | OR6K3 | OR6M1 | OR6N1 | OR6N2 | OR6P1 | OR6Q1 | OR6R2P | OR6S1 | OR6T1 | OR6W1P | OR6X1 | OR6Y1 | OR7A10 | OR7A17 | OR7A5 | OR7C1 | OR7C2