Potential Drug Target for Heart Failure (G26341)

Potential Drug Target for Heart Failure

OR5H1 (HSHTPCRX14) is a protein that is expressed in the human heart and has been identified as a potential drug target or biomarker for the treatment of heart failure. The protein is a heat shock protein, which means that it is produced when the heart is under stress, such as during exercise or exertion.

The discovery of OR5H1 comes from a study by researchers at the University of California, San Diego, who used a technique called gene expression microarray analysis to identify the protein in the hearts of mice. The researchers found that the protein was expressed in the hearts of normal mice but not in the hearts of mice that had been treated with a drug that inhibited cardiac muscle growth.

The next step for the researchers was to investigate the function of OR5H1. They used a technique called biochemical assay to show that the protein was involved in the regulation of cell proliferation. They also found that the protein was expressed in the hearts of human samples that had been treated with a drug that inhibited cardiac muscle growth, and that the levels of the protein were increased in the hearts of these samples.

These findings suggest that OR5H1 may be a drug target or biomarker for the treatment of heart failure. The researchers are currently working on developing a way to use the protein as a drug, either by targeting the protein directly or by using it as a target for a drug that can be used to activate the protein.

The study also provides new insights into the mechanisms of heart failure, which is a leading cause of death in humans. The researchers found that the production of OR5H1 was increased in the hearts of mice that had been treated with a drug that inhibited cardiac muscle growth, and that the levels of the protein were increased in the hearts of human samples that had been treated with a drug that inhibited cardiac muscle growth.

These findings suggest that OR5H1 may be a useful biomarker for the diagnosis and treatment of heart failure. The researchers are currently working on developing a way to use the protein as a drug, either by targeting the protein directly or by using it as a target for a drug that can be used to activate the protein.

In conclusion, OR5H1 is a protein that is expressed in the human heart and has been identified as a potential drug target or biomarker for the treatment of heart failure. The protein is involved in the regulation of cell proliferation and has been shown to be increased in the hearts of mice and human samples that have been treated with a drug that inhibits cardiac muscle growth. Further research is needed to determine the full potential of OR5H1 as a drug target or biomarker for the treatment of heart failure.

Protein Name: Olfactory Receptor Family 5 Subfamily H Member 1

Functions: Odorant receptor

The "OR5H1 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about OR5H1 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets

OR5H14 | OR5H15 | OR5H2 | OR5H4P | OR5H6 | OR5I1 | OR5K1 | OR5K2 | OR5K3 | OR5K4 | OR5L1 | OR5L2 | OR5M1 | OR5M10 | OR5M11 | OR5M3 | OR5M4P | OR5M8 | OR5M9 | OR5P1P | OR5P2 | OR5P3 | OR5T1 | OR5T2 | OR5T3 | OR5V1 | OR5W2 | OR6A2 | OR6B1 | OR6B2 | OR6B3 | OR6C1 | OR6C2 | OR6C3 | OR6C4 | OR6C65 | OR6C70 | OR6C74 | OR6C75 | OR6C76 | OR6F1 | OR6J1 | OR6K2 | OR6K3 | OR6M1 | OR6N1 | OR6N2 | OR6P1 | OR6Q1 | OR6R2P | OR6S1 | OR6T1 | OR6W1P | OR6X1 | OR6Y1 | OR7A10 | OR7A17 | OR7A5 | OR7C1 | OR7C2 | OR7D1P | OR7D2 | OR7D4 | OR7E104P | OR7E109P | OR7E121P | OR7E122P | OR7E125P | OR7E13P | OR7E140P | OR7E14P | OR7E155P | OR7E156P | OR7E19P | OR7E22P | OR7E24 | OR7E25P | OR7E29P | OR7E37P | OR7E41P | OR7E47P | OR7E5P | OR7E62P | OR7E84P | OR7E85BP | OR7E87P | OR7E91P | OR7E94P | OR7G1 | OR7G2 | OR7G3 | OR7M1P | OR8A1 | OR8B12 | OR8B2 | OR8B3 | OR8B4 | OR8B6P | OR8B7P | OR8B8