Target Name: CKAP2
NCBI ID: G26586
Review Report on CKAP2 Target / Biomarker Content of Review Report on CKAP2 Target / Biomarker
CKAP2
Other Name(s): Cytoskeleton associated protein 2, transcript variant 2 | Cytoskeleton-associated protein 2 (isoform 2) | FLJ10749 | DKFZp686L1238 | Tumor-associated microtubule-associated protein | se20-10 | TMAP | CKAP2 variant 1 | Cytoskeleton associated protein 2 | Tumor- and microtubule-associated protein | LB1 | cytoskeleton associated protein 2 | Cytoskeleton-associated protein 2 | Cytoskeleton associated protein 2, transcript variant 1 | tumor- and microtubule-associated protein | Se20-10 | CKAP2 variant 2 | CTCL tumor antigen se20-10 | Cytoskeleton-associated protein 2 (isoform 1) | CKAP2_HUMAN | tumor-associated microtubule-associated protein

CKAP2: A Potential Drug Target and Biomarker

The cytoskeleton is a complex protein network that is essential for maintaining cellular structure and function. It plays a vital role in cell division, intracellular transport, and mechanical forces that help maintain tissue architecture. Cytoskeleton-associated protein 2 (CKAP2) is a protein that is expressed in various cell types and is involved in the regulation of cytoskeleton dynamics.

CKAP2 is a member of the family of cytoskeleton-associated proteins (CAPs), which are known to play a critical role in the regulation of cytoskeleton dynamics and structure. CAPs are involved in the formation and stability of the cytoskeleton, and they are thought to be involved in a wide range of cellular processes, including cell division, intracellular transport, and mechanical forces that help maintain tissue architecture.

CKAP2 is a 21-kDa protein that is expressed in various cell types, including neurons, muscle cells, and red blood cells. It is involved in the regulation of cytoskeleton dynamics and has been shown to play a role in the regulation of cell division, intracellular transport, and mechanical forces that help maintain tissue architecture.

One of the key functions of CKAP2 is its role in the regulation of cytoskeleton dynamics. CKAP2 is involved in the formation and stability of the microtubules, which are the protein structures that make up the cytoskeleton. It does this by interacting with the microtubule-associated protein 2 (MAP2), which is also a CAP that is expressed in various cell types.

MAP2 is known to play a critical role in the regulation of cytoskeleton dynamics, and it is thought to be involved in the regulation of microtubule stability and dynamics. CKAP2 and MAP2 are thought to work together to regulate the formation and stability of microtubules, which is important for the regulation of cellular processes that are critical for cell survival and growth.

Another function of CKAP2 is its role in the regulation of cell division. CKAP2 is involved in the regulation of cell division by affecting the distribution of the microtubules in the cell. It does this by interacting with the protein kinesin, which is involved in the regulation of cell division.

CKAP2 is also involved in the regulation of intracellular transport. CKAP2 is thought to play a role in the regulation of the distribution of intracellular organelles in the cell, including the distribution of the mitochondria and the endoplasmic reticulum. This is important for the regulation of cellular processes that are critical for cell survival and growth.

In addition to its role in the regulation of cytoskeleton dynamics and cell division, CKAP2 is also involved in the regulation of mechanical forces that help maintain tissue architecture. CKAP2 is thought to play a role in the regulation of the distribution of cytoskeleton fibers in the tissue, which is important for the regulation of mechanical forces that help maintain tissue architecture.

CKAP2 is also a potential biomarker for a variety of diseases. For example, CKAP2 has been shown to be involved in the regulation of the development and progression of various diseases, including cancer. Additionally, CKAP2 has been shown to be involved in the regulation of inflammation, which is a critical factor in the development of many diseases.

In conclusion, CKAP2 is a protein that is involved in the regulation of cytoskeleton dynamics and has been shown to play a role in the regulation of cell division, intracellular transport, and mechanical forces that help maintain tissue architecture. CKAP2 is also a potential drug target and biomarker for a variety of diseases. Further research is needed to fully understand the role of CKAP2 in these processes and to develop effective treatments for these diseases.

Protein Name: Cytoskeleton Associated Protein 2

Functions: Possesses microtubule stabilizing properties. Involved in regulating aneuploidy, cell cycling, and cell death in a p53/TP53-dependent manner (By similarity)

The "CKAP2 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about CKAP2 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets

CKAP2L | CKAP4 | CKAP5 | CKB | CKLF | CKM | CKMT1A | CKMT1B | CKMT2 | CKMT2-AS1 | CKS1B | CKS1BP2 | CKS1BP5 | CKS1BP6 | CKS1BP7 | CKS2 | CLASP1 | CLASP2 | CLASRP | Class III phosphatidylinositol 3-kinase (PI3-kinase) sub-complex | Clathrin | CLBA1 | CLC | CLCA1 | CLCA2 | CLCA3P | CLCA4 | CLCC1 | CLCF1 | CLCN1 | CLCN2 | CLCN3 | CLCN4 | CLCN5 | CLCN6 | CLCN7 | CLCNKA | CLCNKB | CLDN1 | CLDN10 | CLDN10-AS1 | CLDN11 | CLDN12 | CLDN14 | CLDN14-AS1 | CLDN15 | CLDN16 | CLDN17 | CLDN18 | CLDN19 | CLDN2 | CLDN20 | CLDN22 | CLDN23 | CLDN24 | CLDN25 | CLDN3 | CLDN34 | CLDN4 | CLDN5 | CLDN6 | CLDN7 | CLDN8 | CLDN9 | CLDND1 | CLDND2 | Cleavage and polyadenylation specificity factor complex | Cleavage factor Im complex | Cleavage Stimulation Factor | CLEC10A | CLEC11A | CLEC12A | CLEC12A-AS1 | CLEC12B | CLEC14A | CLEC16A | CLEC17A | CLEC18A | CLEC18B | CLEC18C | CLEC19A | CLEC1A | CLEC1B | CLEC2A | CLEC2B | CLEC2D | CLEC2L | CLEC3A | CLEC3B | CLEC4A | CLEC4C | CLEC4D | CLEC4E | CLEC4F | CLEC4G | CLEC4GP1 | CLEC4M | CLEC4OP | CLEC5A | CLEC6A