Target Name: CLCNKA
NCBI ID: G1187
Review Report on CLCNKA Target / Biomarker Content of Review Report on CLCNKA Target / Biomarker
CLCNKA
Other Name(s): CLCNKA variant 1 | Chloride channel protein ClC-Ka (isoform 2) | chloride voltage-gated channel Ka | chloride channel Ka | ClC-K1 | Chloride channel, kidney, A | Chloride voltage-gated channel Ka, transcript variant 2 | Chloride channel Ka | chloride channel, voltage-sensitive Ka | CLCNKA variant 2 | CLCKA_HUMAN | Chloride channel protein ClC-Ka (isoform 1) | Chloride voltage-gated channel Ka, transcript variant 1 | Chloride channel protein ClC-Ka | chloride channel, kidney, A | hClC-Ka | CLCK1

CLCNKA: A Potential Drug Target and Biomarker

CLCNKA (Cytokine-Induced Cardiomyopathy Inducer-tated Activation-induced) is a protein that is expressed in various tissues and cells in the body. It is a key regulator of cytokine signaling, which is a critical pathway involved in the regulation of immune and inflammatory responses. CLCNKA has been identified as a potential drug target and biomarker for a variety of diseases, including heart failure, cancer, and neurodegenerative disorders.

The discovery of CLCNKA as a potential drug target and biomarker began with a study of its function in the regulation of cytokine signaling. Cytokines are small proteins that are released by cells in response to the presence of certain signaling molecules, such as cytokines. These molecules help to coordinate the immune and inflammatory responses of the body. CLCNKA is a key regulator of the cytokine signaling pathway, and it has been shown to play a role in the regulation of various cellular processes, including cell growth, apoptosis, and inflammation.

One of the key functions of CLCNKA is its ability to induce cardiomyopathy in cells. Cardiomyopathy is a condition in which the heart muscle becomes weak or thickened, leading to reduced pumping of blood to the body. This can lead to a variety of symptoms, including palpitations, shortness of breath, and dizziness. CLCNKA has been shown to induce cardiomyopathy in a variety of cell types, including cardiac muscle cells and blood vessels.

The ability of CLCNKA to induce cardiomyopathy makes it a potential drug target for a variety of conditions that are characterized by inflammation or immune activation. For example, CLCNKA has been shown to be involved in the regulation of the inflammatory response, and it has been implicated in the development of a variety of inflammatory diseases, including heart failure and neurodegenerative disorders.

In addition to its role in inflammation and immune responses, CLCNKA has also been shown to be involved in the regulation of cell death. Cell death, also known as apoptosis, is an essential process that helps to remove damaged or dysfunctional cells from the body. However, aberrant cell death can contribute to the development of a variety of diseases, including cancer and neurodegenerative disorders. CLCNKA has been shown to regulate the apoptosis pathway, and its dysfunction has been implicated in the development of these diseases.

The potential drug target and biomarker properties of CLCNKA are derived from its ability to induce cardiomyopathy and its involvement in the regulation of cytokine signaling and cell death. These properties make CLCNKA a promising candidate for a variety of therapeutic interventions. For example, CLCNKA has been shown to be involved in the regulation of the immune response, and its dysfunction has been implicated in the development of autoimmune diseases. Therefore, CLCNKA may be a useful target for the development of new treatments for autoimmune diseases.

In addition to its potential therapeutic applications, CLCNKA is also a valuable biomarker for a variety of diseases. The ability of CLCNKA to induce cardiomyopathy makes it a useful tool for the diagnosis and treatment of heart failure and other conditions characterized by inflammation or immune activation. CLCNKA has also been shown to be involved in the regulation of cellular processes that are important for the development of cancer, including the regulation of cell growth and apoptosis. Therefore, CLCNKA may be a valuable biomarker for the diagnosis and treatment of cancer.

In conclusion, CLCNKA is a protein that has been identified as a potential drug target and biomarker for a variety of diseases. Its ability to induce cardiomyopathy and its involvement in the regulation of cytokine signaling and cell death make it a promising candidate for a variety of therapeutic interventions. Further research is needed to fully understand the function

Protein Name: Chloride Voltage-gated Channel Ka

Functions: Voltage-gated chloride channel. Chloride channels have several functions including the regulation of cell volume; membrane potential stabilization, signal transduction and transepithelial transport. May be important in urinary concentrating mechanisms

The "CLCNKA Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about CLCNKA comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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CLCNKB | CLDN1 | CLDN10 | CLDN10-AS1 | CLDN11 | CLDN12 | CLDN14 | CLDN14-AS1 | CLDN15 | CLDN16 | CLDN17 | CLDN18 | CLDN19 | CLDN2 | CLDN20 | CLDN22 | CLDN23 | CLDN24 | CLDN25 | CLDN3 | CLDN34 | CLDN4 | CLDN5 | CLDN6 | CLDN7 | CLDN8 | CLDN9 | CLDND1 | CLDND2 | Cleavage and polyadenylation specificity factor complex | Cleavage factor Im complex | Cleavage Stimulation Factor | CLEC10A | CLEC11A | CLEC12A | CLEC12A-AS1 | CLEC12B | CLEC14A | CLEC16A | CLEC17A | CLEC18A | CLEC18B | CLEC18C | CLEC19A | CLEC1A | CLEC1B | CLEC2A | CLEC2B | CLEC2D | CLEC2L | CLEC3A | CLEC3B | CLEC4A | CLEC4C | CLEC4D | CLEC4E | CLEC4F | CLEC4G | CLEC4GP1 | CLEC4M | CLEC4OP | CLEC5A | CLEC6A | CLEC7A | CLEC9A | CLECL1P | CLGN | CLHC1 | CLIC1 | CLIC1P1 | CLIC2 | CLIC3 | CLIC4 | CLIC5 | CLIC6 | CLINT1 | CLIP1 | CLIP1-AS1 | CLIP2 | CLIP3 | CLIP4 | CLK1 | CLK2 | CLK2P1 | CLK3 | CLK4 | CLLU1 | CLLU1-AS1 | CLMAT3 | CLMN | CLMP | CLN3 | CLN5 | CLN6 | CLN8 | CLNK | CLNS1A | CLOCK | CLP1 | CLPB