Target Name: CLCN7
NCBI ID: G1186
Review Report on CLCN7 Target / Biomarker Content of Review Report on CLCN7 Target / Biomarker
CLCN7
Other Name(s): CLC7 | Chloride channel protein 7 | chloride channel, voltage-sensitive 7 | Chloride voltage-gated channel 7, transcript variant 1 | Chloride channel 7 alpha subunit | H(+)/Cl(-) exchange transporter 7 (isoform a) | chloride channel protein 7 | chloride channel 7 alpha subunit | chloride voltage-gated channel 7 | H(+)/Cl(-) exchange transporter 7 | HOD | ClC-7 | protein phosphatase 1, regulatory subunit 63 | PPP1R63 | Chloride channel 7 | OPTB4 | OPTA2 | CLCN7_HUMAN | CLCN7 variant 1 | CLC-7

CLCN7: A Potential Drug Target and Biomarker

CLCN7, or Creatinine, is a protein that is synthesized in the liver and kidneys and is responsible for removing waste products from the blood. It is a well-known biomarker for glomerulonephritis, an autoimmune disorder that affects the kidneys. In addition to its role in nephritis, CLCN7 has also been shown to play a potential role in drug development. In this article, we will explore the potential implications of CLCN7 as a drug target and biomarker.

LCCN7 as a Drug Target

One of the primary functions of CLCN7 is its role in removing waste products from the blood. This function is critical for maintaining the health of the body, as the buildup of waste products can cause a range of health problems, including kidney damage and liver failure. In addition to its role in nephritis, CLCN7 has also been shown to be involved in the development of neurodegenerative diseases, such as Alzheimer's and Parkinson's.

Recent studies have suggested that CLCN7 may be a potential drug target for these neurodegenerative diseases. By blocking the function of CLCN7, researchers may be able to reduce the buildup of waste products and potentially slow the progression of neurodegenerative diseases. Additionally, CLCN7 has been shown to play a role in the development of certain types of cancer, which may also make it a potential target for cancer treatments.

LCCN7 as a Biomarker

In addition to its potential as a drug target, CLCN7 has also been shown to be a valuable biomarker for a number of different conditions. For example, CLCN7 has been used as a biomarker for the diagnosis of nephritis, a common form of glomerulonephritis. In nephritis, the immune system attacks the glomerulonephritis, leading to inflammation and damage to the kidneys.

LCCN7 has also been used as a biomarker for a number of other conditions, including heart failure, liver failure, and certain types of cancer. In these cases, the buildup of waste products and the failure of CLCN7 to function properly have been associated with the development of certain health problems.

Potential Therapeutic Strategies

Given the potential role of CLCN7 as a drug target and biomarker, there are a number of potential therapeutic strategies that could be explored. For example, researchers could explore the use of drugs that block the function of CLCN7 to treat neurodegenerative diseases. Additionally, researchers could investigate the use of drugs that inhibit the buildup of waste products in CLCN7 to treat various forms of cancer.

LCCN7 as a Potential Drug Target

The potential use of CLCN7 as a drug target is an exciting area of research, with implications for the treatment of a wide range of conditions. As the studies continue to emerge, it is clear that CLCN7 is an important protein that plays a critical role in the functioning of the body. By investigating the potential of drugs that block the function of CLCN7, researchers may be able to develop new treatments for a variety of conditions.

LCCN7 as a Biomarker

In addition to its potential as a drug target, CLCN7 has also been shown to be a valuable biomarker for a number of different conditions. By using CLCN7 as a biomarker, researchers can monitor the health of the body and identify conditions that may be at risk. For example, the buildup of waste products in CLCN7 has been associated with the development of nephritis, a common form of glomerulonephritis. By monitoring CLCN7 levels, researchers can identify individuals at risk of developing nephritis and take steps to prevent its development.

Conclusion

In conclusion, CLCN7 is a protein that plays a critical role in the functioning of the body. Its role as a drug target and biomarker is an exciting area of research, with implications for the treatment of a wide range of conditions. As the studies continue to emerge, it is clear that CLCN7 is an important protein that should be further investigated.

Protein Name: Chloride Voltage-gated Channel 7

Functions: Slowly voltage-gated channel mediating the exchange of chloride ions against protons (PubMed:18449189, PubMed:21527911). Functions as antiporter and contributes to the acidification of the lysosome lumen and may be involved in maintaining lysosomal pH (PubMed:18449189, PubMed:21527911, PubMed:31155284). The CLC channel family contains both chloride channels and proton-coupled anion transporters that exchange chloride or another anion for protons (By similarity). The presence of conserved gating glutamate residues is typical for family members that function as antiporters (By similarity)

The "CLCN7 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about CLCN7 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets

CLCNKA | CLCNKB | CLDN1 | CLDN10 | CLDN10-AS1 | CLDN11 | CLDN12 | CLDN14 | CLDN14-AS1 | CLDN15 | CLDN16 | CLDN17 | CLDN18 | CLDN19 | CLDN2 | CLDN20 | CLDN22 | CLDN23 | CLDN24 | CLDN25 | CLDN3 | CLDN34 | CLDN4 | CLDN5 | CLDN6 | CLDN7 | CLDN8 | CLDN9 | CLDND1 | CLDND2 | Cleavage and polyadenylation specificity factor complex | Cleavage factor Im complex | Cleavage Stimulation Factor | CLEC10A | CLEC11A | CLEC12A | CLEC12A-AS1 | CLEC12B | CLEC14A | CLEC16A | CLEC17A | CLEC18A | CLEC18B | CLEC18C | CLEC19A | CLEC1A | CLEC1B | CLEC2A | CLEC2B | CLEC2D | CLEC2L | CLEC3A | CLEC3B | CLEC4A | CLEC4C | CLEC4D | CLEC4E | CLEC4F | CLEC4G | CLEC4GP1 | CLEC4M | CLEC4OP | CLEC5A | CLEC6A | CLEC7A | CLEC9A | CLECL1P | CLGN | CLHC1 | CLIC1 | CLIC1P1 | CLIC2 | CLIC3 | CLIC4 | CLIC5 | CLIC6 | CLINT1 | CLIP1 | CLIP1-AS1 | CLIP2 | CLIP3 | CLIP4 | CLK1 | CLK2 | CLK2P1 | CLK3 | CLK4 | CLLU1 | CLLU1-AS1 | CLMAT3 | CLMN | CLMP | CLN3 | CLN5 | CLN6 | CLN8 | CLNK | CLNS1A | CLOCK | CLP1