Clec6a: A Protein Involved in Many Cellular Processes (G93978)

Target Name: CLEC6A

NCBI ID: G93978

CLEC6A

Clec6a: A Protein Involved in Many Cellular Processes

clec6a, a member of the C-type lectin domain family 6, plays a crucial role in many cellular processes. It is a protein that is expressed in various cell types, including epithelial, endothelial, and hematopoietic cells. clec6a is known to interact with various protein partners, including tyrosine, which is a chemical that can modulate cell signaling pathways.

One of the key functions of clec6a is its role in cell adhesion. Adhesion is the process by which cells stick together to form tissues and organs. clec6a is involved in this process by helping to regulate the stickiness of cells to each other. This is important for many different cellular processes, including the development and maintenance of tissues and organs, and the regulation of embryonic development.

Another function of clec6a is its role in cell signaling. Many proteins use tyrosine to signal to each other and to their downstream targets. clec6a is one of the proteins that can be regulated by tyrosine. When tyrosine levels are increased, clec6a can interact with various protein partners and modulate their activity. This is important for many different cellular processes, including the regulation of cell growth, differentiation, and survival.

Clec6a is also involved in the regulation of inflammation. Many diseases, including cancer, are characterized by chronic inflammation. clec6a is involved in the regulation of inflammation by helping to regulate the activation and function of immune cells. This is important for protecting against the development and progression of many different diseases.

In addition to its role in cell adhesion, signaling, and inflammation, clec6a is also involved in the regulation of cell cycle progression. The cell cycle is the process by which cells grow, divide, and replicate themselves. clec6a is involved in regulating the length of the cell cycle by helping to control the movement of chromosomes along the DNA. This is important for the regulation of cell growth and the development of cancer.

Clec6a is also involved in the regulation of cellular signaling pathways. Many signaling pathways involve the interaction of proteins with various protein partners. clec6a is one of the proteins that can be regulated by these protein partners, and when clec6a is regulated by these interactions, it can modulate the activity of downstream targets. This is important for the regulation of many different cellular processes, including the regulation of cell growth, differentiation, and survival.

In conclusion, clec6a is a protein that is involved in many different cellular processes. Its functions include cell adhesion, signaling, inflammation, and cell cycle regulation. clec6a is also involved in the regulation of downstream targets, and it is potential drug target for many diseases. Further research is needed to fully understand the role of clec6a in cellular processes and its potential as a drug target.

Protein Name: C-type Lectin Domain Containing 6A

Functions: Calcium-dependent lectin that acts as a pattern recognition receptor (PRR) of the innate immune system: specifically recognizes and binds alpha-mannans on C.albicans hypheas (PubMed:23911656, PubMed:28652405). Binding of C.albicans alpha-mannans to this receptor complex leads to phosphorylation of the immunoreceptor tyrosine-based activation motif (ITAM) of FCER1G, triggering activation of SYK, CARD9 and NF-kappa-B, consequently driving maturation of antigen-presenting cells and shaping antigen-specific priming of T-cells toward effector T-helper 1 and T-helper 17 cell subtypes (By similarity). Recognizes also, in a mannose-dependent manner, allergens from house dust mite and fungi, by promoting cysteinyl leukotriene production (By similarity). Recognizes soluble elements from the eggs of Shistosoma mansoni altering adaptive immune responses (By similarity)

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•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
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•   the target screening and validation;
•   expression level;
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•   related combination drugs;
•   pharmacochemistry experiments;
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•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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