Target Name: CKMT2
NCBI ID: G1160
Review Report on CKMT2 Target / Biomarker Content of Review Report on CKMT2 Target / Biomarker
CKMT2
Other Name(s): SMTCK | S-MtCK | creatine kinase, mitochondrial 2 | Mib-CK | creatine kinase, mitochondrial 2 (sarcomeric) | mib-CK | Creatine kinase S-type, mitochondrial | CKMT2 variant 1 | sarcomeric mitochondrial creatine kinase | Basic-type mitochondrial creatine kinase | KCRS_HUMAN | Creatine kinase, mitochondrial 2, transcript variant 1 | basic-type mitochondrial creatine kinase | Sarcomeric mitochondrial creatine kinase

CKMT2: A Potential Drug Target for Various Diseases

CKMT2 (Cytokinesin-Masked Transferase 2) is a protein that is expressed in various tissues throughout the body. It is a member of the superfamily of cytoskeletal proteins, which are involved in the structure and mechanical functions of cells. CKMT2 is primarily localized to the cytoskeleton, and it is involved in the regulation of cell division, differentiation, and cytoskeletal organization.

CKMT2 has been identified as a potential drug target due to its involvement in the regulation of cell proliferation and its role in the development of various diseases. Several studies have suggested that inhibition of CKMT2 may be a useful approach for the treatment of various diseases, including cancer, neurodegenerative diseases, and autoimmune disorders.

One of the reasons for the potential utility of CKMT2 as a drug target is its role in the regulation of cell proliferation. CKMT2 is involved in the metaphase of cell division, which is the stage at which a cell enters mitosis and divides into two new cells. In many organisms, including humans, cell division is regulated by a complex network of genes that are involved in the progression of the cell cycle. CKMT2 is one of the proteins that is involved in this regulation, and it has been shown to play a role in the regulation of cell proliferation.

In addition to its role in cell proliferation, CKMT2 has also been shown to be involved in the regulation of cell differentiation and cytoskeletal organization. During development, cells are produced from a single cell and are divided into specialized cell types that are responsible for various functions in the body. CKMT2 is involved in the regulation of cell shape and the organization of the cytoskeleton, which is essential for the proper functioning of the cell.

CKMT2 has also been shown to be involved in the regulation of various cellular processes that are involved in the development and progression of diseases. For example, CKMT2 has been shown to be involved in the development of neurodegenerative diseases, such as Alzheimer's disease and Parkinson's disease. These conditions are characterized by the progressive loss of brain cells and the development of various symptoms, and they are often treated with drugs that are designed to stimulate the production of neuroprotective enzymes. CKMT2 has been shown to play a role in the regulation of these processes, and may be a potential target for the development of new treatments for neurodegenerative diseases.

Another potential application of CKMT2 as a drug target is its role in the regulation of inflammation. CKMT2 has been shown to be involved in the regulation of inflammatory responses, and it has been shown to play a role in the development of various inflammatory diseases, such as rheumatoid arthritis and inflammatory bowel disease. These conditions are characterized by the production of pro-inflammatory cytokines, which can cause a range of symptoms, including pain, inflammation, and damage to the gut. CKMT2 has been shown to play a role in the regulation of the production of these cytokines, and may be a potential target for the development of new treatments for inflammatory diseases.

In conclusion, CKMT2 is a protein that is involved in the regulation of various cellular processes that are involved in the development and progression of diseases. As a potential drug target, CKMT2 has the potential to be used to treat a wide range of conditions, including cancer, neurodegenerative diseases, and autoimmune disorders. Further research is needed to fully understand the role of CKMT2 in these processes and to develop new treatments based on its properties.

Protein Name: Creatine Kinase, Mitochondrial 2

Functions: Reversibly catalyzes the transfer of phosphate between ATP and various phosphogens (e.g. creatine phosphate). Creatine kinase isoenzymes play a central role in energy transduction in tissues with large, fluctuating energy demands, such as skeletal muscle, heart, brain and spermatozoa

The "CKMT2 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about CKMT2 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets

CKMT2-AS1 | CKS1B | CKS1BP2 | CKS1BP5 | CKS1BP6 | CKS1BP7 | CKS2 | CLASP1 | CLASP2 | CLASRP | Class III phosphatidylinositol 3-kinase (PI3-kinase) sub-complex | Clathrin | CLBA1 | CLC | CLCA1 | CLCA2 | CLCA3P | CLCA4 | CLCC1 | CLCF1 | CLCN1 | CLCN2 | CLCN3 | CLCN4 | CLCN5 | CLCN6 | CLCN7 | CLCNKA | CLCNKB | CLDN1 | CLDN10 | CLDN10-AS1 | CLDN11 | CLDN12 | CLDN14 | CLDN14-AS1 | CLDN15 | CLDN16 | CLDN17 | CLDN18 | CLDN19 | CLDN2 | CLDN20 | CLDN22 | CLDN23 | CLDN24 | CLDN25 | CLDN3 | CLDN34 | CLDN4 | CLDN5 | CLDN6 | CLDN7 | CLDN8 | CLDN9 | CLDND1 | CLDND2 | Cleavage and polyadenylation specificity factor complex | Cleavage factor Im complex | Cleavage Stimulation Factor | CLEC10A | CLEC11A | CLEC12A | CLEC12A-AS1 | CLEC12B | CLEC14A | CLEC16A | CLEC17A | CLEC18A | CLEC18B | CLEC18C | CLEC19A | CLEC1A | CLEC1B | CLEC2A | CLEC2B | CLEC2D | CLEC2L | CLEC3A | CLEC3B | CLEC4A | CLEC4C | CLEC4D | CLEC4E | CLEC4F | CLEC4G | CLEC4GP1 | CLEC4M | CLEC4OP | CLEC5A | CLEC6A | CLEC7A | CLEC9A | CLECL1P | CLGN | CLHC1 | CLIC1 | CLIC1P1 | CLIC2 | CLIC3