Target Name: INPP5J
NCBI ID: G27124
Review Report on INPP5J Target / Biomarker Content of Review Report on INPP5J Target / Biomarker
INPP5J
Other Name(s): Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A (isoform a) | Inositol polyphosphate-5-phosphatase J, transcript variant 1 | Inositol polyphosphate-5-phosphatase J, transcript variant 3 | Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A (isoform c) | PI5PA_HUMAN | INPP5J variant 3 | INPP5J variant 1 | inositol polyphosphate-5-phosphatase J | Inositol polyphosphate-5-phosphatase J | OTTHUMP00000199393 | PIB5PA | Inositol polyphosphate 5-phosphatase J | OTTHUMP00000199392 | INPP5 | MGC129984 | PIPP | OTTHUMP00000199394 | Phosphatidylinositol (4,5) bisphosphate 5-phosphatase, A | Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A | OTTHUMP00000199391

INPP5J: A Protein Involved in Many Cellular Processes

INPP5J, also known as Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A (isoform a), is a protein that is expressed in various tissues throughout the body. It is a key enzyme in the PI3K/Akt signaling pathway, which is involved in a wide range of cellular processes, including cell signaling, migration, and invasion. INPP5J has also been shown to be involved in the regulation of inflammation and pain.

The PI3K/Akt signaling pathway is a complex intracellular signaling pathway that is involved in the regulation of many cellular processes. It is composed of several key components, including the protein kinase Akt, the protein phosphatidylinositol 4,5-bisphosphate (PIP2), and the protein INPP5J. INPP5J is the protein that is responsible for breaking down PIP2, which is a key signaling molecule in the pathway.

The INPP5J enzyme is involved in the regulation of many different cellular processes, including cell signaling, migration, and invasion. It has been shown to be involved in the regulation of cell proliferation, differentiation, and survival. INPP5J has also been shown to be involved in the regulation of angiogenesis, which is the process by which new blood vessels are formed.

In addition to its role in cell signaling and angiogenesis, INPP5J has also been shown to be involved in the regulation of pain and inflammation. It has been shown to play a key role in the regulation of pain perception and the production of pain signals. INPP5J has also been shown to be involved in the regulation of inflammation, both at the level of systemic inflammation and at the level of local inflammation.

Given its involvement in so many cellular processes, INPP5J is a potential drug target. Many drugs that are currently in use are designed to inhibit the activity of INPP5J, with the goal of treating a wide range of diseases. For example, inhibitors of INPP5J have been shown to be effective in treating a variety of conditions, including cancer, neurodegenerative diseases, and autoimmune disorders.

In addition to its potential as a drug target, INPP5J is also a potential biomarker. The activity of INPP5J can be easily measured and correlated with other biological variables, such as disease severity, treatment response, and patient survival. This makes it a promising biomarker for a variety of diseases, including cancer, neurodegenerative diseases, and autoimmune disorders.

Overall, INPP5J is a protein that is involved in many important cellular processes and has been shown to be involved in the regulation of a wide range of diseases. As a result, it is a promising drug target and a potential biomarker for a variety of diseases. Further research is needed to fully understand the role of INPP5J in cellular processes and its potential as a drug and biomarker.

Protein Name: Inositol Polyphosphate-5-phosphatase J

Functions: Inositol 5-phosphatase, which converts inositol 1,4,5-trisphosphate to inositol 1,4-bisphosphate. Also converts phosphatidylinositol 4,5-bisphosphate to phosphatidylinositol 4-phosphate and inositol 1,3,4,5-tetrakisphosphate to inositol 1,3,4-trisphosphate in vitro. May be involved in modulation of the function of inositol and phosphatidylinositol polyphosphate-binding proteins that are present at membranes ruffles

The "INPP5J Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about INPP5J comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets

INPP5K | INPPL1 | INS | INS-IGF2 | INSC | INSIG1 | INSIG2 | INSL3 | INSL4 | INSL5 | INSL6 | INSM1 | INSM2 | INSR | INSRR | Insulin-like growth factor | Insulin-like growth factor 2 mRNA binding protein | Insulin-like growth factor 2 mRNA-binding protein 1 (isoform 2) | Insulin-like growth factor-binding protein | INSYN1 | INSYN2A | INSYN2B | Integrator complex | Integrin alpha1beta1 (VLA-1) receptor | Integrin alpha2beta1 (VLA-2) receptor | Integrin alpha2beta3 Receptor | Integrin alpha3beta1 receptor | Integrin alpha4beta1 (VLA-4) receptor | Integrin alpha4beta7 (LPAM-1) receptor | Integrin alpha5beta1 (VLA-5) receptor | Integrin alpha5beta3 receptor | Integrin alpha6beta1 Receptor | Integrin alpha6beta4 receptor | Integrin alpha7beta1 Receptor | Integrin alpha9beta1 receptor | Integrin alphaEbeta7 receptor | Integrin alphaLbeta2 (LFA-1) receptor | Integrin alphaMbeta2 (MAC-1) Receptor | Integrin alphavbeta1 | Integrin alphavbeta3 (vitronectin) receptor | Integrin alphavbeta5 receptor | Integrin alphavbeta6 receptor | Integrin alphavbeta8 Receptor | Integrin Receptor | Integrin-linked kinase | Interferon | Interferon-alpha (IFN-alpha) | Interferon-gamma Receptor | Interleukin 17 | Interleukin 21 receptor complex | Interleukin 23 complex (IL-23) | Interleukin 35 | Interleukin-1 | Interleukin-1 receptor-associated kinase (IRAK) | Interleukin-12 (IL-12) | Interleukin-18 Receptor Complex | Interleukin-27 (IL-27) Complex | Interleukin-39 (IL-39) | Interleukin-7 receptor | Intraflagellar transport complex | Intraflagellar transport complex A | Intraflagellar transport complex B | Intrinsic Tenase Complex | INTS1 | INTS10 | INTS11 | INTS12 | INTS13 | INTS14 | INTS15 | INTS2 | INTS3 | INTS4 | INTS4P1 | INTS4P2 | INTS5 | INTS6 | INTS6L | INTS6L-AS1 | INTS6P1 | INTS7 | INTS8 | INTS9 | INTU | Invariant T Cell Receptor | INVS | Inward Rectifier Potassium Channel | IP6K1 | IP6K2 | IP6K3 | IPCEF1 | IPMK | IPO11 | IPO11-LRRC70 | IPO13 | IPO4 | IPO5 | IPO7 | IPO8 | IPO9