Target Name: INTS13
NCBI ID: G55726
Review Report on INTS13 Target / Biomarker Content of Review Report on INTS13 Target / Biomarker
INTS13
Other Name(s): INT13_HUMAN | FLJ10637 | SPATA30 | NET48 | GCT1 | sarcoma antigen NY-SAR-95 | asunder, spermatogenesis regulator homolog (Drosphila) | Cell cycle regulator Mat89Bb homolog | integrator complex subunit 13 | protein asunder homolog | C12orf11 | cell cycle regulator Mat89Bb homolog | ASUN | Germ cell tumor 1 | FLJ10630 | Integrator complex subunit 13 | Sarcoma antigen NY-SAR-95 | germ cell tumor 1 | Mat89Bb | spermatogenesis associated 30

INTS13: A Promising Drug Target for Cell Signaling Pathways

INTS13 (Integrin-like protein 13) is a protein that is expressed in various tissues throughout the body. It is a member of the integrin family, which is a group of transmembrane proteins that play a critical role in cell-cell and cell-extracellular matrix interactions. INTS13 is unique because it is highly conserved across various species, and it has been implicated in many different cellular processes.

One of the most promising aspects of INTS13 is its potential as a drug target. INTS13 has been shown to play a role in many different processes in the body, including cell adhesion, migration, and invasion. It is also involved in the regulation of cell signaling pathways, which is important for many different cellular processes.

One of the ways that INTS13 has been shown to be involved in cell signaling is through its role in the FGF signaling pathway. FGF (fibroblast growth factor) is a protein that is involved in the regulation of cellular growth and differentiation. INTS13 has been shown to play a role in the FGF signaling pathway by regulating the activity of the FGF receptor. This means that INTS13 may be a useful drug target for diseases that are caused by the over- or under-activity of the FGF signaling pathway.

Another way that INTS13 has been shown to be involved in cell signaling is through its role in the TGF-β signaling pathway. TGF-β (transforming growth factor beta) is a protein that is involved in the regulation of cellular growth and differentiation. INTS13 has been shown to play a role in the TGF-β signaling pathway by regulating the activity of the TGF-β receptor. This means that INTS13 may be a useful drug target for diseases that are caused by the over- or under-activity of the TGF-β signaling pathway.

In addition to its role in the FGF and TGF-β signaling pathways, INTS13 has also been shown to be involved in many other cellular processes. For example, INTS13 has been shown to play a role in the regulation of cell adhesion, which is important for the proper functioning of many different tissues. It may also be involved in the regulation of cell migration and invasion, which are important for the proper functioning of many different tissues.

Overall, INTS13 is a protein that has been shown to play a role in many different cellular processes. Its unique conserved nature and involvement in cell signaling pathways make it a promising candidate as a drug target. Further research is needed to fully understand the role of INTS13 in the body and its potential as a drug.

Protein Name: Integrator Complex Subunit 13

Functions: Crucial regulator of the mitotic cell cycle and development. At prophase, required for dynein anchoring to the nuclear envelope important for proper centrosome-nucleus coupling. At G2/M phase, may be required for proper spindle formation and execution of cytokinesis. Probable component of the Integrator (INT) complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3'-box-dependent processing (PubMed:23904267)

The "INTS13 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about INTS13 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets

INTS14 | INTS15 | INTS2 | INTS3 | INTS4 | INTS4P1 | INTS4P2 | INTS5 | INTS6 | INTS6L | INTS6L-AS1 | INTS6P1 | INTS7 | INTS8 | INTS9 | INTU | Invariant T Cell Receptor | INVS | Inward Rectifier Potassium Channel | IP6K1 | IP6K2 | IP6K3 | IPCEF1 | IPMK | IPO11 | IPO11-LRRC70 | IPO13 | IPO4 | IPO5 | IPO7 | IPO8 | IPO9 | IPO9-AS1 | IPP | IPPK | IPW | IQCA1 | IQCA1L | IQCB1 | IQCC | IQCD | IQCE | IQCF1 | IQCF2 | IQCF3 | IQCF5-AS1 | IQCF6 | IQCG | IQCH | IQCH-AS1 | IQCJ | IQCJ-SCHIP1 | IQCK | IQCM | IQCN | IQGAP1 | IQGAP2 | IQGAP3 | IQSEC1 | IQSEC2 | IQSEC3 | IQSEC3P3 | IQUB | IRAG1 | IRAG1-AS1 | IRAG2 | IRAK1 | IRAK1BP1 | IRAK2 | IRAK3 | IRAK4 | IREB2 | IRF1 | IRF1-AS1 | IRF2 | IRF2BP1 | IRF2BP2 | IRF2BPL | IRF3 | IRF4 | IRF5 | IRF6 | IRF7 | IRF8 | IRF9 | IRGC | IRGM | IRGQ | IRS1 | IRS2 | IRS4 | IRX1 | IRX2 | IRX2-DT | IRX3 | IRX4 | IRX5 | IRX6 | ISCA1 | ISCA1P1