Target Name: INTS14
NCBI ID: G81556
Review Report on INTS14 Target / Biomarker Content of Review Report on INTS14 Target / Biomarker
INTS14
Other Name(s): INT14_HUMAN | DKFZp564O1664 | INTS14 variant 4 | Integrator complex subunit 14, transcript variant 4 | C15orf44 | integrator complex subunit 14 | VWA9 | Integrator complex subunit 14 | von Willebrand factor A domain-containing protein 9 | von Willebrand factor A domain containing 9 | UPF0464 protein C15orf44 | Integrator complex subunit 14 isoform 4 | OTTHUMP00000164211

INTS14 Regulates IGF Signaling Pathway

INTS14, also known as INTS14-HUMAN, is a protein that is expressed in various tissues of the human body, including the brain, heart, and kidneys. It is a member of the IMP family, which includes proteins involved in the intracellular signaling pathway known as the insulin-like growth factor (IGF) signaling pathway.

The IGF signaling pathway is a critical pathway involved in the growth, development, and survival of various tissues in the body. It is a highly conserved pathway that is involved in the regulation of cell proliferation, differentiation, and survival. The IGF signaling pathway has been implicated in the development and progression of many diseases, including cancer, obesity, and neurodegenerative disorders.

INTS14 is a key protein that is involved in the IGF signaling pathway. It is a 14-kDa protein that is expressed in various tissues of the human body, including the brain, heart, and kidneys. It is a potent regulator of IGF signaling, and its levels have been shown to be involved in the regulation of cellular processes such as cell growth, differentiation, and survival.

One of the key functions of INTS14 is its ability to inhibit the activity of the IGF1 receptor, which is a key component of the IGF signaling pathway. The IGF1 receptor is a transmembrane protein that is involved in the regulation of cellular processes such as cell growth, differentiation, and survival. It is a potent regulator of cell proliferation, and has been implicated in the development and progression of many diseases, including cancer.

INTS14 has been shown to inhibit the activity of the IGF1 receptor by a process known as phosphorylation. Phosphorylation is a process in which the protein phosphate groups on a protein are added, which can modulate its activity. INTS14 is a potent inhibitor of the IGF1 receptor, and its ability to do so has been shown to play a key role in the regulation of cellular processes such as cell growth, differentiation, and survival.

Another function of INTS14 is its ability to regulate the activity of the IGF2 receptor, which is another key component of the IGF signaling pathway. The IGF2 receptor is a transmembrane protein that is involved in the regulation of cellular processes such as cell growth, differentiation, and survival. It is a potent regulator of cell proliferation, and has been implicated in the development and progression of many diseases, including cancer.

INTS14 has been shown to regulate the activity of the IGF2 receptor by a process known as phosphorylation. Phosphorylation is a process in which the protein phosphate groups on a protein are added, which can modulate its activity. INTS14 is a potent regulator of the IGF2 receptor, and its ability to do so has been shown to play a key role in the regulation of cellular processes such as cell growth, differentiation, and survival.

In addition to its role in regulating the IGF signaling pathway, INTS14 has also been shown to play a key role in the regulation of cellular processes such as cell adhesion, migration, and survival. It is a member of the IMP family, which includes proteins involved in the intracellular signaling pathway known as the insulin-like growth factor (IGF) signaling pathway.

The IGF signaling pathway is a critical pathway involved in the growth, development, and survival of various tissues in the body. It is a highly conserved pathway that is involved in the regulation of cell proliferation, differentiation, and survival. The IGF signaling pathway has been implicated in the development and progression of many diseases, including cancer, obesity, and neurodegenerative disorders.

INTS14 is a key protein that is involved in the IGF signaling pathway. It is a 14-kDa protein that is expressed in various tissues of the human body, including the brain, heart, and kidneys. It is a potent regulator of IGF signaling, and its levels have been shown to be involved in the regulation of cellular processes such as cell growth, differentiation, and survival.

Protein Name: Integrator Complex Subunit 14

Functions: Probable component of the Integrator (INT) complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3'-box-dependent processing

The "INTS14 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about INTS14 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets

INTS15 | INTS2 | INTS3 | INTS4 | INTS4P1 | INTS4P2 | INTS5 | INTS6 | INTS6L | INTS6L-AS1 | INTS6P1 | INTS7 | INTS8 | INTS9 | INTU | Invariant T Cell Receptor | INVS | Inward Rectifier Potassium Channel | IP6K1 | IP6K2 | IP6K3 | IPCEF1 | IPMK | IPO11 | IPO11-LRRC70 | IPO13 | IPO4 | IPO5 | IPO7 | IPO8 | IPO9 | IPO9-AS1 | IPP | IPPK | IPW | IQCA1 | IQCA1L | IQCB1 | IQCC | IQCD | IQCE | IQCF1 | IQCF2 | IQCF3 | IQCF5-AS1 | IQCF6 | IQCG | IQCH | IQCH-AS1 | IQCJ | IQCJ-SCHIP1 | IQCK | IQCM | IQCN | IQGAP1 | IQGAP2 | IQGAP3 | IQSEC1 | IQSEC2 | IQSEC3 | IQSEC3P3 | IQUB | IRAG1 | IRAG1-AS1 | IRAG2 | IRAK1 | IRAK1BP1 | IRAK2 | IRAK3 | IRAK4 | IREB2 | IRF1 | IRF1-AS1 | IRF2 | IRF2BP1 | IRF2BP2 | IRF2BPL | IRF3 | IRF4 | IRF5 | IRF6 | IRF7 | IRF8 | IRF9 | IRGC | IRGM | IRGQ | IRS1 | IRS2 | IRS4 | IRX1 | IRX2 | IRX2-DT | IRX3 | IRX4 | IRX5 | IRX6 | ISCA1 | ISCA1P1 | ISCA2