Target Name: LGSN
NCBI ID: G51557
Review Report on LGSN Target / Biomarker Content of Review Report on LGSN Target / Biomarker
LGSN
Other Name(s): LGSN_HUMAN | OTTHUMP00000016673 | Glutamate-ammonia ligase domain-containing protein 1 | LGSN variant X2 | Lengsin, lens protein with glutamine synthetase domain, transcript variant X2 | MGC163240 | OTTHUMP00000016672 | glutamate-ammonia ligase domain-containing protein 1 | LGSN variant 2 | glutamate-ammonia ligase (glutamine synthase) domain containing 1 | Lens glutamine synthase-like | Lengsin | LGS | Lengsin (isoform b) | Lengsin, lens protein with glutamine synthetase domain, transcript variant 1 | GLULD1 | Glutamate-ammonia ligase (glutamine synthase) domain containing 1 | Lengsin (isoform a) | MGC163238 | lengsin, lens protein with glutamine synthetase domain | Lengsin, lens protein with glutamine synthetase domain, transcript variant 2 | LGSN variant 1

Understanding LGSN: Potential Drug Target Or Biomarker

LGSN (Ligase-conjugated subunit of human nuclease G) is a protein that is expressed in various cell types of the human body. It is a key enzyme in the DNA repair pathway, which is responsible for repairing damage to DNA that can occur due to factors such as UV radiation, radiation, and other forms of stress.LGSN is an essential protein that helps maintain the integrity of genetic material and is critical for the proper functioning of numerous cellular processes in the body.

Recent studies have identified LGSN as a potential drug target or biomarker, which could be used to treat a variety of diseases. One of the main reasons for its potential as a drug target is its involvement in the DNA repair pathway. Many diseases, such as cancer, are caused by changes in the DNA that can no longer be repaired by the body. By targeting LGSN and encouraging it to function properly, it may be possible to prevent or reverse these changes and potentially treat these diseases.

Additionally, LGSN has been shown to be involved in a variety of cellular processes that are important for maintaining tissue health and function. For example, it is involved in the regulation of cell growth, differentiation, and the immune response. It also plays a role in the production of certain signaling molecules, such as TGF-β1, which is important for cell survival and growth.

Another potential use of LGSN as a drug target is its role in the development of certain diseases. For example, some studies have suggested that LGSN may be involved in the development of certain types of cancer, such as breast cancer. Additionally, LGSN has been shown to be involved in the development of neurodegenerative diseases, such as Alzheimer's disease and Parkinson's disease.

In addition to its potential as a drug target, LGSN has also been identified as a potential biomarker for a variety of diseases. For example, some studies have suggested that LGSN may be involved in the development of certain types of cancer, such as breast cancer, and that it may be a useful biomarker for tracking the effectiveness of certain treatments.

One of the main challenges in studying LGSN as a drug target or biomarker is its complex structure and function. LGSN is a large protein that is expressed in a variety of cell types and is involved in many different cellular processes. It is also involved in the production of a variety of signaling molecules, which makes it difficult to study.

Despite these challenges, researchers are making progress in understanding the role of LGSN in cellular processes and its potential as a drug target or biomarker. Recent studies have shown that LGSN plays a role in the regulation of cell growth, differentiation, and the immune response, and that it is involved in the production of certain signaling molecules. Additionally, some studies have suggested that LGSN may be involved in the development of certain types of cancer and in the regulation of certain signaling pathways.

In conclusion, LGSN is a protein that is expressed in various cell types of the human body and is involved in the DNA repair pathway. It has been identified as a potential drug target or biomarker for a variety of diseases, including cancer and neurodegenerative diseases. Further research is needed to fully understand its role in cellular processes and its potential as a therapeutic agent.

Protein Name: Lengsin, Lens Protein With Glutamine Synthetase Domain

Functions: May act as a component of the cytoskeleton or as a chaperone for the reorganization of intermediate filament proteins during terminal differentiation in the lens. Does not seem to have enzymatic activity (By similarity)

The "LGSN Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about LGSN comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets

LHB | LHCGR | LHFPL1 | LHFPL2 | LHFPL3 | LHFPL3-AS1 | LHFPL3-AS2 | LHFPL4 | LHFPL5 | LHFPL6 | LHFPL7 | LHPP | LHX1 | LHX2 | LHX3 | LHX4 | LHX4-AS1 | LHX5 | LHX6 | LHX8 | LHX9 | LIAS | LIF | LIFR | LIFR-AS1 | LIG1 | LIG3 | LIG4 | LILRA1 | LILRA2 | LILRA3 | LILRA4 | LILRA5 | LILRA6 | LILRB1 | LILRB2 | LILRB3 | LILRB4 | LILRB5 | LILRP1 | LILRP2 | LIM domain kinase (LIMK) | LIM2 | LIMA1 | LIMASI | LIMCH1 | LIMD1 | LIMD1-AS1 | LIMD2 | LIME1 | LIMK1 | LIMK2 | LIMS1 | LIMS2 | LIMS3 | LIMS3-LOC440895 | LIMS4 | LIN28A | LIN28B | LIN28B-AS1 | LIN37 | LIN52 | LIN54 | LIN7A | LIN7B | LIN7C | LIN9 | LINC-PINT | LINC-ROR | LINC00028 | LINC00029 | LINC00032 | LINC00051 | LINC00052 | LINC00092 | LINC00102 | LINC00106 | LINC00111 | LINC00112 | LINC00113 | LINC00114 | LINC00115 | LINC00158 | LINC00159 | LINC00160 | LINC00161 | LINC00163 | LINC00173 | LINC00174 | LINC00184 | LINC00189 | LINC00200 | LINC00205 | LINC00207 | LINC00208 | LINC00210 | LINC00221 | LINC00222 | LINC00226 | LINC00235