Target Name: MED4
NCBI ID: G29079
Review Report on MED4 Target / Biomarker Content of Review Report on MED4 Target / Biomarker
MED4
Other Name(s): VDRIP | MED4 variant 1 | Mediator of RNA polymerase II transcription subunit 4 (isoform 1) | mediator, 34-kD subunit, homolog | OTTHUMP00000018390 | DRIP36 | Vitamin D3 receptor-interacting protein complex 36 kDa component | TRAP/SMCC/PC2 subunit p36 subunit | Mediator of RNA polymerase II transcription, subunit 4 homolog | Mediator complex subunit 4, transcript variant 1 | FLJ10956 | Mediator complex subunit 4 | RP11-90M2.2 | OTTHUMP00000018392 | ARC36 | vitamin D3 receptor-interacting protein complex 36 kDa component | Mediator of RNA polymerase II transcription subunit 4 | activator-recruited cofactor 36 kDa component | TRAP36 | mediator complex subunit 4 | OTTHUMP00000018391 | HSPC126 | MED4_HUMAN | Activator-recruited cofactor 36 kDa component | vitamin D receptor-interacting protein, 36-kD

MED4 as A Drug Target Or Biomarker

MED4 (Methionylated Enkeleukine Kinase 4) is a protein that is expressed in various tissues throughout the body, including the brain, lungs, heart, kidneys, and intestines. It is a key regulator of cell growth, differentiation, and survival, and is involved in the development and progression of many diseases, including cancer.

In recent years, researchers have been interested in investigating the potential of MED4 as a drug target or biomarker. MED4 has been shown to play a role in a variety of cellular processes, including cell signaling, DNA replication, and stress response. It has also has been shown to interact with several other proteins, including T-cell receptor tyrosine kinase (TCR), which is a protein that is involved in cell signaling and immune response.

One potential mechanism by which MED4 could be targeted as a drug is through its role in cell signaling. MED4 has been shown to play a negative role in cell signaling by regulating the activity of several signaling pathways, including the T-cell signaling pathway. This suggests that targeting MED4 could be a way to treat T-cell-related diseases, such as cancer.

Another potential mechanism by which MED4 could be targeted as a drug is through its role in stress response. MED4 has been shown to play a role in the regulation of cellular stress responses, which are important for maintaining cellular homeostasis and responding to environmental stressors. This suggests that targeting MED4 could be a way to treat stress-related diseases, such as neurodegenerative disorders.

In addition to its potential as a drug target, MED4 has also been shown to be a potential biomarker for several diseases. For example, MED4 has been shown to be expressed in several types of cancer, including breast, lung, and ovarian cancer. This suggests that targeting MED4 could be a way to diagnose and treat these cancers.

Targeting MED4 as a drug or biomarker is still in the early stages of research, and more studies are needed to fully understand its potential and to develop effective treatments. However, the potential of MED4 as a drug target or biomarker is an exciting area of 鈥嬧?媟esearch , and one that could lead to new treatments for a variety of diseases.

Protein Name: Mediator Complex Subunit 4

Functions: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors

The "MED4 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about MED4 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets

MED4-AS1 | MED6 | MED7 | MED8 | MED9 | MEDAG | Mediator Complex | Mediator of RNA Polymerase II Transcription | MEF2A | MEF2B | MEF2C | MEF2C-AS1 | MEF2C-AS2 | MEF2D | MEFV | MEG3 | MEG8 | MEG9 | MEGF10 | MEGF11 | MEGF6 | MEGF8 | MEGF9 | MEI1 | MEI4 | MEIG1 | MEIKIN | MEIOB | MEIOC | MEIOSIN | MEIS1 | MEIS1-AS2 | MEIS1-AS3 | MEIS2 | MEIS3 | MEIS3P1 | MEIS3P2 | Melanin | Melanin-concentrating hormone (MCH) receptor | Melanocortin receptor | Melanoma-Associated Antigen | Melatonin receptor | MELK | MELTF | MELTF-AS1 | Membrane-Bound Protein Tyrosine Phosphatases (rPTPs) | Membrane-spanning 4-domains subfamily A member 4A | MEMO1 | MEMO1P1 | MEMO1P4 | MEMO1P5 | MEN1 | MEOX1 | MEOX2 | MEP1A | MEP1AP2 | MEP1AP4 | MEP1B | MEPCE | MEPE | MERTK | MESD | MESP1 | MESP2 | MEST | MESTIT1 | MESTP3 | MESTP4 | MET | Metabotropic glutamate (mGluR) receptor | Metallothionein | METAP1 | METAP1D | METAP2 | Metaxin complex | Methionine adenosyltransferase | Methionine adenosyltransferase II | Methionyl aminopeptidase | Methylcytosine dioxygenase (TET) | METRN | METRNL | METTL1 | METTL13 | METTL14 | METTL15 | METTL15P1 | METTL15P2 | METTL16 | METTL17 | METTL18 | METTL21A | METTL21C | METTL21EP | METTL22 | METTL23 | METTL24 | METTL25 | METTL25B | METTL26 | METTL27