Target Name: MELTF
NCBI ID: G4241
Review Report on MELTF Target / Biomarker Content of Review Report on MELTF Target / Biomarker
MELTF
Other Name(s): MAP97 | Melanotransferrin | MELTF variant 1 | TRFM_HUMAN | MTF1 | MTf | MFI2 | CD228 | antigen p97 (melanoma associated) identified by monoclonal antibodies 133.2 and 96.5 | Melanotransferrin (isoform 1) | Melanotransferrin, transcript variant 1 | Melanoma-associated antigen p97 | membrane-bound transferrin-like protein | melanotransferrin

MELTF: A Protein Implicated in Neurodegenerative and Inflammatory Diseases

MELTF (MAP97) is a protein that is expressed in various tissues of the body, including the brain, heart, and kidneys. It is a key regulator of cell signaling pathways and has been implicated in a number of neurodegenerative diseases. In recent years, researchers have been investigating MELTF as a potential drug target or biomarker for a variety of conditions, including Alzheimer's disease, Parkinson's disease, and several others.

One of the main reasons for the interest in MELTF is its role in cell signaling pathways. MELTF has been shown to play a key role in the regulation of neurotransmitter signaling, particularly in the production and release of dopamine. Dopamine is a neurotransmitter that is involved in a variety of physiological processes, including mood regulation, motivation, and movement. MELTF has been shown to play a key role in the regulation of dopamine release and has been implicated in the development and progression of several neurodegenerative diseases, including Alzheimer's disease and Parkinson's disease.

Another reason for the interest in MELTF is its role in the regulation of inflammation. MELTF has been shown to play a key role in the regulation of immune cell function and has been implicated in the development of several inflammatory diseases, including multiple sclerosis and rheumatoid arthritis. In addition, MELTF has been shown to play a key role in the regulation of inflammation-related signaling pathways, including the production and release of pro-inflammatory cytokines.

In addition to its role in cell signaling pathways and inflammation, MELTF has also been shown to play a key role in the regulation of cellular processes that are important for maintaining cellular structure and homeostasis. MELTF has been shown to play a key role in the regulation of cell division, cell growth, and cell death. In addition, MELTF has been shown to play a key role in the regulation of cell-cell adhesion, which is important for maintaining the integrity of tissues and organs.

Given the multiple roles that MELTF has been shown to play in cellular processes, it is not surprising that researchers have been interested in investigating it as a potential drug target or biomarker. In recent years, a number of studies have demonstrated the potential of MELTF as a drug target for a variety of conditions, including Alzheimer's disease, Parkinson's disease, and several others.

One of the main potential benefits of investigating MELTF as a drug target is its potential to treat a variety of neurodegenerative diseases. MELTF has been shown to play a key role in the regulation of dopamine signaling pathways, which are involved in the development and progression of several neurodegenerative diseases, including Alzheimer's disease and Parkinson's disease. By targeting MELTF, researchers may be able to develop new treatments for these conditions.

Another potential benefit of investigating MELTF as a drug target is its potential to treat a variety of inflammatory diseases. MELTF has been shown to play a key role in the regulation of immune cell function and has been implicated in the development of several inflammatory diseases, including multiple sclerosis and rheumatoid arthritis. By targeting MELTF, researchers may be able to develop new treatments for these conditions.

In addition to its potential therapeutic applications, MELTF has also been shown to be a potential biomarker for a variety of conditions. By measuring the levels of MELTF in brain tissue, researchers may be able to use MELTF as a diagnostic tool for neurodegenerative diseases, including Alzheimer's disease and Parkinson's disease. In addition, MELTF has been shown to play a key role in the regulation of cellular processes that are important for maintaining cellular

Protein Name: Melanotransferrin

Functions: Involved in iron cellular uptake. Seems to be internalized and then recycled back to the cell membrane. Binds a single atom of iron per subunit. Could also bind zinc

The "MELTF Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about MELTF comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets

MELTF-AS1 | Membrane-Bound Protein Tyrosine Phosphatases (rPTPs) | Membrane-spanning 4-domains subfamily A member 4A | MEMO1 | MEMO1P1 | MEMO1P4 | MEMO1P5 | MEN1 | MEOX1 | MEOX2 | MEP1A | MEP1AP2 | MEP1AP4 | MEP1B | MEPCE | MEPE | MERTK | MESD | MESP1 | MESP2 | MEST | MESTIT1 | MESTP3 | MESTP4 | MET | Metabotropic glutamate (mGluR) receptor | Metallothionein | METAP1 | METAP1D | METAP2 | Metaxin complex | Methionine adenosyltransferase | Methionine adenosyltransferase II | Methionyl aminopeptidase | Methylcytosine dioxygenase (TET) | METRN | METRNL | METTL1 | METTL13 | METTL14 | METTL15 | METTL15P1 | METTL15P2 | METTL16 | METTL17 | METTL18 | METTL21A | METTL21C | METTL21EP | METTL22 | METTL23 | METTL24 | METTL25 | METTL25B | METTL26 | METTL27 | METTL2A | METTL2B | METTL3 | METTL4 | METTL5 | METTL6 | METTL7A | METTL7B | METTL8 | METTL9 | MEX3A | MEX3B | MEX3C | MEX3D | MFAP1 | MFAP2 | MFAP3 | MFAP3L | MFAP4 | MFAP5 | MFF | MFF-DT | MFGE8 | MFHAS1 | MFN1 | MFN2 | MFNG | MFRP | MFSD1 | MFSD10 | MFSD11 | MFSD12 | MFSD13A | MFSD14A | MFSD14B | MFSD14CP | MFSD2A | MFSD2B | MFSD3 | MFSD4A | MFSD4A-AS1 | MFSD4B | MFSD4B-DT | MFSD5