Target Name: MESD
NCBI ID: G23184
Review Report on MESD Target / Biomarker Content of Review Report on MESD Target / Biomarker
MESD
Other Name(s): mesoderm development LRP chaperone MESD | mesoderm development candidate 2 | KIAA0081 | OI20 | BOCA | Mesoderm development LRP chaperone MESD | Mesoderm development candidate 2 | Mesoderm development protein | mesoderm development LRP chaperone | mesoderm development protein | LDLR chaperone MESD | MESD_HUMAN | renal carcinoma antigen NY-REN-61 | MESD variant 1 | MESDC2 | Renal carcinoma antigen NY-REN-61 | Mesoderm development LRP chaperone, transcript variant 1 | LRP chaperone MESD

MESD: A Potential Drug Target Or Biomarker

MESD (Mesoderm Development LRP Chaperone) is a protein that plays a crucial role in the development and maintenance of mesoderm, which is a type of tissue found in the body that is responsible for creating all of the different types of skin. MESD is a protein that is expressed in high levels in the skin and other tissues, and it is thought to be involved in the regulation of cell proliferation and differentiation.

Recent studies have suggested that MESD may be a potential drug target or biomarker for a variety of diseases, including cancer, neurodegenerative diseases, and autoimmune disorders. This is because MESD is involved in many important processes in the body, and alterations in its levels or function have been implicated in the development and progression of many different diseases.

One of the key reasons for the interest in MESD as a drug target or biomarker is its role in the regulation of cell proliferation. MESD is a known chaperone, which means that it helps to transport and guide proteins to their destination on the cell surface. This is important for the regulation of cell growth and division, as well as the development and maintenance of tissues.

In addition to its role in cell proliferation, MESD is also involved in the regulation of cell differentiation. During development, cells have to be able to switch between different types of cell fates in order to create the diverse array of tissues that make up the body. MESD helps to facilitate this process by ensuring that proteins that are involved in cell differentiation are properly transported to their destination.

Another potential drug target or biomarker for MESD is its role in the regulation of inflammation. MESD is involved in the production of inflammatory cytokines, which are proteins that are involved in the immune response. In addition, MESD is also thought to be involved in the regulation of the immune response itself, by helping to ensure that T cells and other immune cells are able to recognize and respond to foreign substances in the body.

In conclusion, MESD is a protein that plays a crucial role in the development and maintenance of mesoderm, as well as many other important biological processes in the body. Its function as a chaperone and its involvement in cell proliferation, differentiation, and inflammation make it an attractive target for drug development and research into the underlying causes of many different diseases. Further studies are needed to fully understand the role of MESD in these processes and to identify its potential as a drug or biomarker.

Protein Name: Mesoderm Development LRP Chaperone

Functions: Chaperone specifically assisting the folding of beta-propeller/EGF modules within the family of low-density lipoprotein receptors (LDLRs) (PubMed:15014448). Acts as a modulator of the Wnt pathway through chaperoning the coreceptors of the canonical Wnt pathway, LRP5 and LRP6, to the plasma membrane (PubMed:17488095). Essential for specification of embryonic polarity and mesoderm induction. Plays an essential role in neuromuscular junction (NMJ) formation by promoting cell-surface expression of LRP4 (By similarity). May regulate phagocytosis of apoptotic retinal pigment epithelium (RPE) cells (By similarity)

The "MESD Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about MESD comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets

MESP1 | MESP2 | MEST | MESTIT1 | MESTP3 | MESTP4 | MET | Metabotropic glutamate (mGluR) receptor | Metallothionein | METAP1 | METAP1D | METAP2 | Metaxin complex | Methionine adenosyltransferase | Methionine adenosyltransferase II | Methionyl aminopeptidase | Methylcytosine dioxygenase (TET) | METRN | METRNL | METTL1 | METTL13 | METTL14 | METTL15 | METTL15P1 | METTL15P2 | METTL16 | METTL17 | METTL18 | METTL21A | METTL21C | METTL21EP | METTL22 | METTL23 | METTL24 | METTL25 | METTL25B | METTL26 | METTL27 | METTL2A | METTL2B | METTL3 | METTL4 | METTL5 | METTL6 | METTL7A | METTL7B | METTL8 | METTL9 | MEX3A | MEX3B | MEX3C | MEX3D | MFAP1 | MFAP2 | MFAP3 | MFAP3L | MFAP4 | MFAP5 | MFF | MFF-DT | MFGE8 | MFHAS1 | MFN1 | MFN2 | MFNG | MFRP | MFSD1 | MFSD10 | MFSD11 | MFSD12 | MFSD13A | MFSD14A | MFSD14B | MFSD14CP | MFSD2A | MFSD2B | MFSD3 | MFSD4A | MFSD4A-AS1 | MFSD4B | MFSD4B-DT | MFSD5 | MFSD6 | MFSD6L | MFSD8 | MFSD9 | MGA | MGAM | MGAM2 | MGARP | MGAT1 | MGAT2 | MGAT3 | MGAT3-AS1 | MGAT4A | MGAT4B | MGAT4C | MGAT4D | MGAT4EP | MGAT4FP