Understanding The Role of MRPS14 in Disease (G63931)

Target Name: MRPS14

NCBI ID: G63931

MRPS14

Understanding The Role of MRPS14 in Disease

Mitochondrial 28S ribosomal protein S14 (MRPS14) is a protein that plays a crucial role in the structure and function of the mitochondria, which are energy-producing structures found in the cells of most eukaryotes. The mitochondria are responsible for generating the majority of the cell's energy through a process called cellular respiration. This process involves the breakdown of glucose into carbon dioxide and water, releasing a large amount of energy in the form of ATP.

MRPS14 is one of the proteins that forms the mitochondrial ribosome, which is the structure where the instructions for making proteins are translated from mRNA into protein. It is a large protein that contains multiple domains, including a nucleotide-binding domain, a Rossmann-fold domain, and a hypervariable region (HVR). The HVR is a region of the protein that can be targeted by small molecules, such as drugs, and is thought to play a role in modulating the activity of the mitochondrial ribosome.

Despite its importance for cellular respiration, MRPS14 is not well understood, and its function in the context of disease is not well established. However, some studies have suggested that it may be a potential drug target or biomarker for a variety of diseases.

One potential mechanism by which MRPS14 may be involved in disease is its role in the development of certain forms of cancer. In fact, several studies have suggested that high levels of MRPS14 are associated with the development of certain types of cancer, including breast, ovarian, and prostate cancer. This suggests that targeting MRPS14 may be a promising strategy for the development of new cancer therapies.

Another potential mechanism by which MRPS14 may be involved in disease is its role in the treatment of certain neurological conditions. For example, some studies have suggested that MRPS14 may be involved in the development and progression of Alzheimer's disease, a condition in which the brain is affected by a progressive accumulation of neurofibrillary tangles and beta-amyloid plaques. By targeting MRPS14, researchers may be able to develop new treatments for this debilitating condition.

In addition to its potential role in cancer and neurological disease, MRPS14 may also be involved in the development of other conditions. For example, some studies have suggested that MRPS14 may be involved in the development of certain cardiovascular conditions, such as heart failure and hypertension.

Given the importance of MRPS14 in the structure and function of the mitochondria, as well as its potential involvement in the development of disease, there is growing interest in studying its potential as a drug target or biomarker. While more research is needed to fully understand its function and potential, targeting MRPS14 may be a promising strategy for the development of new therapies for a variety of conditions.

Protein Name: Mitochondrial Ribosomal Protein S14

The "MRPS14 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about MRPS14 comprehensively, including but not limited to:
•   general information;
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•   protein biological mechanisms;
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•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
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•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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