Target Name: RPSA
NCBI ID: G3921
Review Report on RPSA Target / Biomarker Content of Review Report on RPSA Target / Biomarker
RPSA
Other Name(s): Laminin receptor 1 (67kD, ribosomal protein SA) | lamR | 37/67 kDa laminin receptor | Colon carcinoma laminin-binding protein | ribosomal protein SA | LRP | 37 kDa laminin receptor precursor | RPSA variant 3 | 67LR | LRP/LR | NEM/1CHD4 | RSSA_HUMAN | 34/67 kDa laminin receptor | 37 kDa laminin receptor | Multidrug resistance-associated protein MGr1-Ag | LBP/p40 | Laminin receptor 1 | p40 | RPSA variant 1 | laminin receptor 1 (67kD, ribosomal protein SA) | LAMR1 | LAMBR | ICAS | 40S ribosomal protein SA | 67kD, ribosomal protein SA | multidrug resistance-associated protein MGr1-Ag | Laminin-binding protein precursor p40 | colon carcinoma laminin-binding protein | SA | Small ribosomal subunit protein uS2 | 67 kDa laminin receptor | LBP | Laminin receptor | small ribosomal subunit protein uS2 | Ribosomal protein SA (Laminin receptor) | 40S ribosomal protein SA (isoform 2) | 37LRP | laminin-binding protein precursor p40 | Ribosomal protein SA | 40S ribosomal protein SA (isoform 1) | LamR

RPSA: A Potential Drug Target Or Biomarker

The laminin receptor 1 (LRP1) is a transmembrane protein that plays a crucial role in cell-cell adhesion and tissue organization. It is a member of the laminin subfamily, which is characterized by the presence of a unique N-terminal domain that is involved in protein-protein interactions and the formation of complex structures. LRP1 is expressed in various tissues and cell types, including epithelial, mesenchymal, and neural cells.

The discovery of RPSA (ribosomal protein SA) as a potential drug target or biomarker for various diseases has generated significant interest in the study of laminin biology and its potential clinical applications. RPSA is a 67kD protein that is expressed in various cell types, including cancer cells, and it is involved in the regulation of cell growth, differentiation, and survival.

During the past few years, researchers have made significant progress in the study of RPSA and its functions. One of the most significant findings is the involvement of RPSA in the regulation of cell adhesion and the formation of tight junctions. These structures are critical for maintaining tissue integrity and are often disrupted in diseases such as cancer, neurodegenerative diseases, and developmental disorders.

In addition to its role in cell adhesion, RPSA is also involved in the regulation of cell signaling pathways. It has been shown to play a role in the regulation of theNotch signaling pathway, which is involved in the regulation of cell growth, differentiation, and survival. RPSA has also been shown to be involved in the regulation of the TGF-β pathway, which is involved in the regulation of cell growth and differentiation.

The role of RPSA in cancer biology is also of great interest. RPSA has been shown to be involved in the regulation of cancer cell growth and survival. It has been shown to inhibit the migration and invasion of cancer cells and to promote the apoptosis of cancer cells. These effects make RPSA an attractive drug target or biomarker for cancer therapies.

In addition to its potential as a drug target or biomarker, RPSA has also been shown to have potential as a diagnostic tool. The expression of RPSA is often reduced in various types of cancer, which makes it a potential biomarker for cancer diagnosis.

The identification of RPSA as a potential drug target or biomarker has led to a significant increase in the number of studies investigating its role in various diseases. These studies have provided new insights into the functions of RPSA and its potential as a therapeutic agent.

Conclusion

In conclusion, RPSA is a transmembrane protein that plays a crucial role in various cell processes, including cell adhesion, signaling pathways, and cancer biology. Its involvement in these processes makes RPSA an attractive drug target or biomarker for various diseases. The recent studies have provided new insights into the functions of RPSA and its potential as a therapeutic agent. Further research is needed to fully understand the role of RPSA in various diseases and to develop safe and effective therapies based on its use.

Protein Name: Ribosomal Protein SA

Functions: Required for the assembly and/or stability of the 40S ribosomal subunit. Required for the processing of the 20S rRNA-precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits. Also functions as a cell surface receptor for laminin. Plays a role in cell adhesion to the basement membrane and in the consequent activation of signaling transduction pathways. May play a role in cell fate determination and tissue morphogenesis. Acts as a PPP1R16B-dependent substrate of PPP1CA

The "RPSA Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about RPSA comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets

RPSA2 | RPSAP1 | RPSAP12 | RPSAP15 | RPSAP19 | RPSAP20 | RPSAP28 | RPSAP4 | RPSAP41 | RPSAP46 | RPSAP47 | RPSAP48 | RPSAP49 | RPSAP52 | RPSAP55 | RPSAP56 | RPSAP61 | RPSAP70 | RPSAP9 | RPTN | RPTOR | RPUSD1 | RPUSD2 | RPUSD3 | RPUSD4 | RRAD | RRAGA | RRAGB | RRAGC | RRAGD | RRAS | RRAS2 | RRBP1 | RREB1 | RRH | RRM1 | RRM2 | RRM2B | RRM2P3 | RRN3 | RRN3P1 | RRN3P2 | RRN3P3 | RRP1 | RRP12 | RRP15 | RRP1B | RRP36 | RRP7A | RRP7BP | RRP8 | RRP9 | RRS1 | RRS1-DT | RS1 | RSAD1 | RSAD2 | RSBN1 | RSBN1L | RSC1A1 | RSF1 | RSKR | RSL1D1 | RSL1D1-DT | RSL24D1 | RSPH1 | RSPH10B | RSPH14 | RSPH3 | RSPH4A | RSPH6A | RSPH9 | RSPO1 | RSPO2 | RSPO3 | RSPO4 | RSPRY1 | RSRC1 | RSRC2 | RSRP1 | RSU1 | RSU1P2 | RTBDN | RTCA | RTCB | RTEL1 | RTEL1-TNFRSF6B | RTF1 | RTF2 | RTKN | RTKN2 | RTL1 | RTL10 | RTL3 | RTL4 | RTL5 | RTL6 | RTL8A | RTL8B | RTL8C