Target Name: RSBN1
NCBI ID: G54665
Review Report on RSBN1 Target / Biomarker Content of Review Report on RSBN1 Target / Biomarker
RSBN1
Other Name(s): Lysine-specific demethylase 9 | round spermatid basic protein 1 | DKFZp781E21150 | RSBN1 variant 1 | RP11-324J2.1 | ROSBIN | Round spermatid basic protein 1 | OTTHUMP00000013723 | KDM9 | RSBN1_HUMAN | Round spermatid basic protein 1, transcript variant 1

RSBN1: A Potential Drug Target and Biomarker

Recent studies have identified a protein known as RSBN1 (蟻-Sar-NOD) as a potential drug target and biomarker for various diseases, including cancer, neurodegenerative diseases, and autoimmune disorders. RSBN1 is a nuclear protein that is expressed in various tissues and cell types in the body, including the brain, pancreas, and gastrointestinal tract. It is composed of two distinct chains, alpha- and beta-chains, and is characterized by the presence of a unique N-terminus and a C-terminus.

The alpha-chain is the most abundant and well-studied subunit of RSBN1 and is responsible for the protein's nuclear localization, while the beta-chain is thought to play a role in the protein's stability and functions. The N-terminus of RSBN1 is rich in various domains, including a nuclear localization domain (NLD), a GFP-like nuclear-export signal (NES), and a transmembrane region (TMR). These domains are involved in the regulation of nuclear import and export, as well as the interaction with various cellular signaling pathways.

RSBN1 has been shown to be involved in various physiological processes in the body, including cell growth, apoptosis, and inflammation. For example, studies have shown that RSBN1 is involved in the regulation of cell proliferation and has been implicated in the development of cancer. In addition, RSBN1 has also been linked to the regulation of cell apoptosis, which is the process by which cells undergo programmed cell death. This is important for the control of cellular aging and the maintenance of tissue homeostasis.

Another area of interest for RSBN1 is its role in the regulation of inflammation. Inflammation is a critical immune response to tissue damage and can contribute to a variety of diseases, including cancer, neurodegenerative diseases, and autoimmune disorders. Studies have shown that RSBN1 is involved in the regulation of inflammation by controlling the movement of immune cells and promoting the production of pro-inflammatory cytokines.

In addition to its involvement in cellular processes, RSBN1 has also been shown to play a role in the regulation of cellular signaling pathways. For example, RSBN1 has been shown to be involved in the regulation of theNotch signaling pathway, which is involved in the regulation of stem cell self-renewal and differentiation. In addition, RSBN1 has also been shown to be involved in the regulation of the TGF-β signaling pathway, which is involved in the regulation of cell growth and differentiation.

Given its involvement in a variety of cellular processes, RSBN1 has potential as a drug target for a variety of diseases. For example, RSBN1 has been shown to be involved in the regulation of cancer cell proliferation and has been linked to the development of various types of cancer. In addition, RSBN1 has also been shown to be involved in the regulation of neurodegenerative diseases, including Alzheimer's disease and Parkinson's disease. These findings suggest that RSBN1 may be a useful target for the development of new treatments for these diseases.

Furthermore, RSBN1 has also been shown to be involved in the regulation of autoimmune disorders, such as rheumatoid arthritis and multiple sclerosis. These disorders are characterized by the production of autoimmune antibodies that can cause inflammation and damage to various body tissues. Studies have shown that RSBN1 is involved in the regulation of the immune response and has been implicated in the development of autoimmune disorders.

In conclusion, RSBN1 is a protein that has been shown to be involved in a variety of cellular processes in the body. Its unique N-terminus and C-terminus, as well as its richly described NLD, NES, and TMR domains, make it a promising candidate for drug targeting. Studies have shown that RSBN1 is involved in the regulation of cell growth, apoptosis, inflammation, and cellular signaling pathways, making it a potential

Protein Name: Round Spermatid Basic Protein 1

Functions: Histone demethylase that specifically demethylates dimethylated 'Lys-20' of histone H4 (H4K20me2), thereby modulating chromosome architecture

The "RSBN1 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about RSBN1 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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RSBN1L | RSC1A1 | RSF1 | RSKR | RSL1D1 | RSL1D1-DT | RSL24D1 | RSPH1 | RSPH10B | RSPH14 | RSPH3 | RSPH4A | RSPH6A | RSPH9 | RSPO1 | RSPO2 | RSPO3 | RSPO4 | RSPRY1 | RSRC1 | RSRC2 | RSRP1 | RSU1 | RSU1P2 | RTBDN | RTCA | RTCB | RTEL1 | RTEL1-TNFRSF6B | RTF1 | RTF2 | RTKN | RTKN2 | RTL1 | RTL10 | RTL3 | RTL4 | RTL5 | RTL6 | RTL8A | RTL8B | RTL8C | RTL9 | RTN1 | RTN2 | RTN3 | RTN4 | RTN4IP1 | RTN4R | RTN4RL1 | RTN4RL2 | RTP1 | RTP2 | RTP3 | RTP4 | RTP5 | RTRAF | RTTN | RUBCN | RUBCNL | RUFY1 | RUFY2 | RUFY3 | RUFY4 | RUNDC1 | RUNDC3A | RUNDC3A-AS1 | RUNDC3B | RUNX1 | RUNX1-IT1 | RUNX1T1 | RUNX2 | RUNX2-AS1 | RUNX3 | RUNX3-AS1 | RUSC1 | RUSC1-AS1 | RUSC2 | RUSF1 | RUVBL1 | RUVBL1-AS1 | RUVBL2 | RWDD1 | RWDD2A | RWDD2B | RWDD3 | RWDD3-DT | RWDD4 | RXFP1 | RXFP2 | RXFP3 | RXFP4 | RXRA | RXRB | RXRG | RXYLT1 | Ryanodine receptor | RYBP | RYK | RYR1