Target Name: CCSER1
NCBI ID: G401145
Review Report on CCSER1 Target / Biomarker Content of Review Report on CCSER1 Target / Biomarker
CCSER1
Other Name(s): coiled-coil serine rich protein 1 | FAM190A | Coiled-coil serine-rich protein 1 | CCSER1 variant 2 | family with sequence similarity 190, member A | KIAA1680 | Coiled-coil serine rich protein 1, transcript variant 1 | protein FAM190A | Protein FAM190A | Family with sequence similarity 190, member A | CCSE1_HUMAN | Serine-rich coiled-coil domain-containing protein 1 | Serine-rich coiled-coil domain-containing protein 1 (isoform 1) | Serine-rich coiled-coil domain-containing protein 1 (isoform 2) | CCSER1 variant 1 | Coiled-coil serine rich protein 1, transcript variant 2

CCSER1: A Potential Drug Target and Biomarker for Chronic Pain

Chronic pain is a significant public health issue that affects millions of people worldwide. The World Health Organization (WHO) estimates that approximately 10% of the global population experiences chronic pain, with approximately 50% of the population reporting chronic non-cancer pain. Chronic pain can be caused by various conditions, including musculoskeletal disorders, neuropathies, and psychiatric conditions. Despite the availability of treatments for some types of chronic pain, the management of chronic pain remains a significant challenge for healthcare providers.

CCSER1: A Potential Drug Target and Biomarker for Chronic Pain

The protein CCSER1, also known as coiled-coil serine rich protein 1, has been identified as a potential drug target and biomarker for chronic pain. CCSER1 is a protein that is expressed in various tissues and organs, including the brain, spinal cord, and peripheral tissues. It is characterized by a unique coiled-coil structure and is involved in the regulation of a variety of cellular processes, including cell signaling, protein folding, and inflammation.

Recent studies have suggested that CCSER1 may be a drug target for chronic pain due to its involvement in pain signaling. CCSER1 has been shown to interact with various pain molecules, including opioids, capsaicin, and inflammatory cytokines. Additionally, CCSER1 has been shown to modulate the activity of pain-related neural circuits in the brain.

CCSER1 has also been shown to be a potential biomarker for chronic pain. The expression of CCSER1 has been shown to be associated with the development of chronic pain conditions, including osteoarthritis, neuropathic pain, and rheumatoid arthritis. Additionally, CCSER1 has been shown to be expressed in the blood vessels of individuals with chronic pain, which may suggest that it may be a useful biomarker for pain assessment in clinical settings.

The Potential for CCSER1 as a Drug Target

The potential for CCSER1 as a drug target for chronic pain is due to its involvement in pain signaling and its expression in various tissues and organs. CCSER1 has been shown to interact with pain molecules, including opioids, capsaicin, and inflammatory cytokines. Additionally, CCSER1 has been shown to modulate the activity of pain-related neural circuits in the brain, which may indicate that it plays a role in the regulation of pain.

One potential mechanism by which CCSER1 may contribute to pain signaling is through its role in the regulation of pain-related neural circuits in the brain. CCSER1 has been shown to modulate the activity of neural circuits that are involved in pain perception and regulation. For example, studies have shown that CCSER1 can inhibit the activity of GABA-producing neurons, which are involved in pain modulation. Additionally, CCSER1 has been shown to increase the activity of delta- opioid receptors, which are involved in pain perception.

Another potential mechanism by which CCSER1 may contribute to pain signaling is through its role in the regulation of pain-related cytokine production. CCSER1 has been shown to be involved in the production and regulation of pro-inflammatory cytokines, including TNF-alpha, IL-1, and IL-6. These cytokines are involved in the regulation of pain sensitivity and may contribute to the development of chronic pain conditions.

The Potential for CCSER1 as a Biomarker

The potential for CCSER1 as a biomarker for chronic pain is due to its expression in various tissues and organs, including the brain, spinal cord, and peripheral tissues. The expression of CCSER1 has been shown to be associated with the development of chronic pain conditions, including osteoarthritis, neuropathic pain, and rheumatoid arthritis. Additionally, CCSER1 has

Protein Name: Coiled-coil Serine Rich Protein 1

The "CCSER1 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about CCSER1 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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