Target Name: PRRT4
NCBI ID: G401399
Review Report on PRRT4 Target / Biomarker Content of Review Report on PRRT4 Target / Biomarker
PRRT4
Other Name(s): Proline rich transmembrane protein 4, transcript variant 1 | PRRT4_HUMAN | proline rich transmembrane protein 4 | Proline-rich transmembrane protein 4 | PRRT4 variant 1 | Proline-rich transmembrane protein 4 (isoform 1)

PRRT4: A Potential Drug Target and Biomarker

Proline-rich transmembrane protein 4 (PRRT4) is a gene that encodes a protein located at the cell membrane that plays a crucial role in various cellular processes. The protein is expressed in many tissues and organs, including the brain, heart, kidneys, and gastrointestinal tract. It is known for its high proline content, which is unique among proteins.

PRRT4 has been identified as a potential drug target and biomarker due to its unique structure and various functions. The high proline content of PRRT4 makes it an attractive target for small molecules that can modulate its activity. Additionally, the protein's expression is known to be regulated by various signaling pathways, which adds to its potential as a drug target.

One of the key functions of PRRT4 is its role in cell signaling. The protein is involved in several signaling pathways, including G-protein-coupled receptor (GPCR) signaling, neurotrophin signaling, and T-cell signaling. PRRT4 has been shown to play a critical role in these signaling pathways, and alterations in its expression have been linked to various diseases.

In addition to its role in cell signaling, PRRT4 is also involved in several other cellular processes. For example, it is involved in the regulation of ion channels, which are critical for the flow of electrical current through the cell membrane. PRRT4 has also been shown to play a role in the regulation of gene expression, which is important for the development and maintenance of tissues and organs.

The high proline content of PRRT4 also makes it a potential biomarker for several diseases. The protein's unique structure and functions make it an attractive target for small molecules that can modulate its activity. For example, small molecules that can bind to PRRT4's proline-rich region have been shown to have therapeutic effects in a variety of diseases, including cancer, neurodegenerative diseases, and autoimmune diseases.

In conclusion, PRRT4 is a gene that has a unique structure and functions that make it an attractive potential drug target and biomarker. Its role in cell signaling and its involvement in several cellular processes make it an important target for small molecules that can modulate its activity. Additionally, its high proline content makes it a potential biomarker for several diseases. Further research is needed to fully understand the role of PRRT4 in disease and to develop effective therapies.

Protein Name: Proline Rich Transmembrane Protein 4

The "PRRT4 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about PRRT4 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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