Target Name: PRTN3
NCBI ID: G5657
Review Report on PRTN3 Target / Biomarker Content of Review Report on PRTN3 Target / Biomarker
PRTN3
Other Name(s): azurophil granule protein 7 | PR-3 | AGP7 | Neutrophil proteinase 4 | Wegener autoantigen | C-ANCA antigen | PMNL proteinase | ACPA | serine proteinase, neutrophil | MBN | leukocyte proteinase 3 | neutrophil proteinase 4 | MBT | proteinase 3 | Leukocyte proteinase 3 | Proteinase 3 | P29 | wegener autoantigen | Myeloblastin | Wegener granulomatosis autoantigen | C-ANCA | NP-4 | PR3 | CANCA | NP4 | PRTN3_HUMAN

PRTN3: Key Protein in Brain and Body Function

PRTN3 (Azurophil Granule Protein 7) is a protein that is expressed in various tissues throughout the body, including the brain, heart, and kidneys. It is a member of the granule protein family, which is a type of protein that is involved in the delivery and processing of nutrients in the body. PRTN3 is also known as APP-1E, and it is produced by the liver.

One of the key functions of PRTN3 is its role in the delivery of nutrients to the brain. The brain is very demanding on nutrients, and it requires a constant supply of oxygen, glucose, and other essential nutrients in order to function properly. PRTN3 is involved in the delivery of these nutrients to the brain, and it is thought to play a key role in the development and maintenance of brain health.

In addition to its role in brain health, PRTN3 is also involved in the regulation of inflammation in the body. inflammation is a natural response of the immune system, but chronic inflammation can be harmful to the body. PRTN3 helps to regulate the production of pro-inflammatory molecules, which are thought to play a key role in the development of many diseases, including heart disease and diabetes.

Another function of PRTN3 is its role in the regulation of blood pressure. Blood pressure is a critical factor that helps to maintain blood flow to the body's tissues. PRTN3 is involved in the regulation of blood pressure by helping to relax blood vessels, which can help to lower blood pressure.

PRTN3 is also involved in the regulation of the immune system. The immune system is a critical part of the body's defense against infection and disease, and it is constantly active in the fight against harmful microorganisms. PRTN3 helps to regulate the production of immune cells, which are thought to play a key role in the development of many diseases.

In addition to its role in immune system regulation, PRTN3 is also involved in the regulation of cellular processes in the body. It is thought to play a key role in the regulation of cell division and the production of new cells, which are essential for the growth and development of tissues.

PRTN3 is also involved in the regulation of the transport of nutrients in the body. It is part of a complex system that helps to transport nutrients from the gut to the bloodstream, where they can be distributed to the body's tissues.

In conclusion, PRTN3 (Azurophil Granule Protein 7) is a protein that is involved in a wide range of important functions in the body. It is produced by the liver and is involved in the delivery of nutrients to the brain, the regulation of inflammation, blood pressure, and the immune system. PRTN3 may be a promising drug target or biomarker for a variety of diseases. Further research is needed to fully understand the role of PRTN3 in the body and its potential as a therapeutic agent.

Protein Name: Proteinase 3

Functions: Serine protease that degrades elastin, fibronectin, laminin, vitronectin, and collagen types I, III, and IV (in vitro) (PubMed:3198760, PubMed:2033050, PubMed:28240246). By cleaving and activating receptor F2RL1/PAR-2, enhances endothelial cell barrier function and thus vascular integrity during neutrophil transendothelial migration (PubMed:23202369). May play a role in neutrophil transendothelial migration, probably when associated with CD177 (PubMed:22266279)

The "PRTN3 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about PRTN3 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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