Target Name: PRUNE1
NCBI ID: G58497
Review Report on PRUNE1 Target / Biomarker Content of Review Report on PRUNE1 Target / Biomarker
PRUNE1
Other Name(s): Drosophila-related expressed sequence 17 | DRES17 | DRES-17 | Prune homolog | H-PRUNE | TcD37 homolog | OTTHUMP00000033020 | NMIHBA | Prune exopolyphosphatase 1, transcript variant 1 | HTcD37 | Protein prune homolog | PRUN1_HUMAN | Protein prune homolog 1 | hPrune | Exopolyphosphatase PRUNE1 | prune exopolyphosphatase 1 | PRUNE | protein prune homolog 1 | HTCD37 | Exopolyphosphatase PRUNE1 (isoform 1) | PRUNE1 variant 1

PRUNE1: A Potential Drug Target Or Biomarker

PRUNE1 (Drosophila-related expressed sequence 17) is a gene that has been identified in the scientific literature as having potential as a drug target or biomarker. The gene is located on the X chromosome and is expressed in the body's tissues and organs, including the brain, heart, and gastrointestinal tract.

PRUNE1 is named after its discovery in the fruit fly, Drosophila. It is a member of the PID family of gene transcription factors, which are known for their role in regulating gene expression in various organisms.

Recent studies have suggested that PRUNE1 may be involved in a wide range of physiological processes in animals, including development, growth, and metabolism. Its expression has been detected in various tissues and organs, including the brain, where it has been shown to be involved in the development and maintenance of neural stem cells.

In addition to its potential role in neural development, PRUNE1 has also been shown to be involved in the regulation of stem cell proliferation and the development of tissues. This suggests that it may be a useful target for drugs that are aimed at preventing or treating cancer, neurodegenerative diseases, or other conditions that involve the over-growth or proliferation of cells.

One of the key challenges in studying PRUNE1 is its relatively high level of expression in the body's tissues, which can make it difficult to study its effects in specific organs or contexts. However, researchers are continuing to investigate the potential role of PRUNE1 in various physiological processes, and are working to develop methods for studying its effects in greater detail.

In addition to its potential as a drug target, PRUNE1 has also been shown to be a potential biomarker for a variety of diseases. For example, some studies have suggested that levels of PRUNE1 expression may be elevated in the brains of individuals with certain neurological conditions, such as Alzheimer's disease or Parkinson's disease.

These findings suggest that PRUNE1 may be an important player in the development and progression of these conditions, and that it may be worth investigating as a potential therapeutic target or biomarker. Further research is needed to fully understand the role of PRUNE1 in these diseases and to develop effective treatments.

In conclusion, PRUNE1 is a gene that has shown promise as a drug target or biomarker. Its expression is involved in a wide range of physiological processes in animals, including neural development and stem cell regulation. Further research is needed to fully understand its role in the development and progression of various diseases and to develop effective treatments.

Protein Name: Prune Exopolyphosphatase 1

Functions: Phosphodiesterase (PDE) that has higher activity toward cAMP than cGMP, as substrate. Plays a role in cell proliferation, migration and differentiation, and acts as a negative regulator of NME1. Plays a role in the regulation of neurogenesis (PubMed:28334956). Involved in the regulation of microtubule polymerization (PubMed:28334956)

The "PRUNE1 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about PRUNE1 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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