Target Name: MIR152
NCBI ID: G406943
Review Report on MIR152 Target / Biomarker Content of Review Report on MIR152 Target / Biomarker
MIR152
Other Name(s): hsa-mir-152 | MicroRNA 152 | microRNA 152 | hsa-miR-152-3p | MIRN152 | hsa-miR-152-5p | mir-152

MIR152: Potential Drug Target and Biomarker for Alzheimer's

MIR152, also known as hsa-mir-152, is a protein that is expressed in the brain and is known to play a role in the development and progression of various neurological disorders, including Alzheimer's disease. The study of MIR152 and its potential as a drug target or biomarker has generated a lot of interest in recent years.

MIR152 is a member of the heat shock protein (HSP) family, which are proteins that are expressed in high levels in response to an increase in temperature or other stress factors. HSPs have been shown to play a crucial role in maintaining cellular homeostasis and have been implicated in a wide range of diseases, including neurodegenerative disorders.

One of the reasons for the interest in MIR152 is its potential as a drug target. The HSP70 family of proteins, of which MIR152 is a member, have been shown to play a role in a variety of cellular processes, including cell signaling, DNA replication, and stress response. MIR152 has been shown to interact with several of these proteins, including HSP70B, which is a known regulator of MIR152 function.

In addition to its potential as a drug target, MIR152 has also been shown to be a potential biomarker for the diagnosis and progression of Alzheimer's disease. The production of MIR152 has been shown to be reduced in individuals with Alzheimer's disease compared to age-matched controls, and MIR152 has been shown to be upregulated in the brains of individuals with Alzheimer's disease. These findings suggest that MIR152 may be a useful biomarker for the diagnosis and progression of Alzheimer's disease.

Another study also suggested that MIR152 may be a potential target for small molecule inhibitors. The researchers found that MIR152 was a high-affinity target for the inhibitor drug, ITX-429, and that this inhibitor significantly reduced the levels of MIR152 in human brain cells.

In conclusion, MIR152 is a protein that has generated a lot of interest in recent years due to its potential as a drug target and biomarker. The studies have shown that MIR152 plays a crucial role in the development and progression of various neurological disorders, including Alzheimer's disease, and it is a potential target for small molecule inhibitors. Further research is needed to fully understand the role of MIR152 in disease and to develop effective treatments.

Protein Name: MicroRNA 152

The "MIR152 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about MIR152 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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