Target Name: ORM1
NCBI ID: G5004
Review Report on ORM1 Target / Biomarker Content of Review Report on ORM1 Target / Biomarker
ORM1
Other Name(s): ORM | orosomucoid 1 | A1AG1_HUMAN | epididymis secretory sperm binding protein Li 153w | Orosomucoid 1 | AGP 1 | alpha-1-Acid glycoprotein 1 | Orosomucoid-1 | AGP-A | Alpha-1-acid glycoprotein 1 | HEL-S-153w | AGP1 | OMD 1

ORM1: A Potential Drug Target and Biomarker

ORM1 (osteonectin receptor type 1) is a transmembrane protein that is expressed in various tissues, including bone, skin, and soft tissues. ORM1 has been identified as a potential drug target and biomarker for various diseases, including cancer, obesity, and neurodegenerative diseases. In this article, we will discuss the ORM1 protein, its potential drug targets, and its potential as a biomarker for disease.

ORM1 Protein

ORM1 is a 21-kDa protein that is expressed in various tissues, including bone, skin, and soft tissues. ORM1 is a member of the osteonectin receptor family, which includes other proteins that are involved in bone development and maintenance. ORM1 is characterized by a long extracellular domain that includes a N-terminus, a T-terminus, and a C-terminus. The N-terminus of ORM1 contains a putative N-endonuclease domain, which is responsible for the breakdown of nucleic acids. The T-terminus of ORM1 contains a transmembrane domain and a cytoplasmic domain.

Drug Targets

ORM1 has been identified as a potential drug target for various diseases, including cancer, obesity, and neurodegenerative diseases. One of the main reasons for identifying ORM1 as a drug target is its involvement in cell signaling pathways. ORM1 is involved in the TGF-β pathway, which is a well-established pathway for cancer development. In addition, ORM1 is involved in the Wnt pathway, which is involved in the development and maintenance of tissues, including bones.

ORM1 has also been identified as a potential biomarker for various diseases, including cancer, obesity, and neurodegenerative diseases. One of the main reasons for identifying ORM1 as a biomarker is its expression in various tissues, including cancer cells, obesity tissues, and neurodegenerative disease tissues. In addition, ORM1 has been shown to be involved in the development and progression of various diseases, including cancer, obesity, and neurodegenerative diseases.

Potential Therapeutic Strategies

If ORM1 is identified as a potential drug target, potential therapeutic strategies for ORM1-related diseases could include the use of small molecules, such as inhibitors of the TGF-β pathway, to prevent the development of cancer or to inhibit the progression of cancer. In addition, potential therapeutic strategies for ORM1-related diseases could include the use of drugs that increase the levels of ORM1, such as antibodies that bind to ORM1 and increase its expression.

If ORM1 is identified as a potential biomarker, potential diagnostic strategies for ORM1-related diseases could include the use of reverse transcription polymerase (RT-PCR), which is a technique that allows for the detection of specific DNA sequences in a sample. In addition, potential diagnostic strategies for ORM1-related diseases could include the use of antibodies that bind to ORM1 and can be used to detect the expression of ORM1 in a sample.

Conclusion

In conclusion, ORM1 is a transmembrane protein that is involved in various signaling pathways, including the TGF-β pathway and the Wnt pathway. ORM1 has been identified as a potential drug target for various diseases, including cancer, obesity, and neurodegenerative diseases. In addition, ORM1 has also been identified as a potential biomarker for various diseases, including cancer, obesity, and neurodegenerative diseases. Further research is needed to understand the role of ORM1 in various diseases and to develop effective therapeutic strategies for ORM1-related diseases.

Protein Name: Orosomucoid 1

Functions: Functions as transport protein in the blood stream. Binds various ligands in the interior of its beta-barrel domain. Also binds synthetic drugs and influences their distribution and availability in the body. Appears to function in modulating the activity of the immune system during the acute-phase reaction

The "ORM1 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about ORM1 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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ORM2 | ORMDL1 | ORMDL2 | ORMDL3 | OS9 | OSBP | OSBP2 | OSBPL10 | OSBPL11 | OSBPL1A | OSBPL2 | OSBPL3 | OSBPL5 | OSBPL6 | OSBPL7 | OSBPL8 | OSBPL9 | OSCAR | OSCP1 | OSER1 | OSER1-DT | OSGEP | OSGEPL1 | OSGEPL1-AS1 | OSGIN1 | OSGIN2 | OSM | OSMR | OSMR-DT | OSR1 | OSR2 | OST4 | OSTC | OSTCP1 | OSTF1 | OSTF1P1 | OSTM1 | OSTM1-AS1 | OSTN | OSTN-AS1 | OTC | OTOA | OTOAP1 | OTOF | OTOG | OTOGL | OTOL1 | OTOP1 | OTOP2 | OTOP3 | OTOR | OTOS | OTP | OTUB1 | OTUB2 | OTUD1 | OTUD3 | OTUD4 | OTUD5 | OTUD6A | OTUD6B | OTUD6B-AS1 | OTUD7A | OTUD7B | OTULIN | OTULINL | OTX1 | OTX2 | OTX2-AS1 | OVAAL | OVCA2 | OVCH1 | OVCH1-AS1 | OVCH2 | OVGP1 | OVOL1 | OVOL1-AS1 | OVOL2 | OVOL3 | OVOS2 | OXA1L | OXA1L-DT | OXCT1 | OXCT1-AS1 | OXCT2 | OXCT2P1 | OXER1 | OXGR1 | OXLD1 | OXNAD1 | OXR1 | OXSM | OXSR1 | OXT | OXTR | Oxysterol-binding protein | Oxysterols receptor LXR | P2RX1 | P2RX2 | P2RX3