OSBPL11: A Potential Drug Target and Biomarker (G114885)

Target Name: OSBPL11

NCBI ID: G114885

OSBPL11

OSBPL11: A Potential Drug Target and Biomarker

OSBPL11 (OSB11_HUMAN) is a protein that is expressed in various tissues of the human body. It is a potential drug target and has been identified as a potential biomarker for various diseases, including cancer.

Background:

OSBPL11 (OSB11_HUMAN) is a member of the superfamily of evolutionarily conserved protein families, known as the OASIS/P6XX superfamily. It is a single-chain protein that contains 11 amino acid residues. OSBPL11 is highly conserved in various species, including humans, and has a calculated pI of 4.89.

Expression:

OSBPL11 is expressed in various tissues of the human body, including the brain, heart, liver, and pancreas. It is also expressed in various cell types, including neurons and immune cells. OSBPL11 is predominantly expressed in the brain, where it is located in the protein secretion pathway.

Drug Target Potential:

OSBPL11 is a potential drug target due to its unique structure and its expression in various tissues of the human body. The conserved nature of OSBPL11 in various species makes it a promising candidate for small molecule inhibitors. Additionally, its expression in the brain suggests that it may play a role in the development and progression of neurodegenerative diseases.

Biomarker Potential:

OSBPL11 has the potential to serve as a biomarker for various diseases, including cancer. Its expression in various tissues of the human body, including the brain, makes it a potential indicator of disease progression. Additionally, its conserved nature suggests that it may be a good candidate for diagnostic biomarkers.

Conclusion:

OSBPL11 is a protein that has the potential to be a drug target or biomarker for various diseases. Its conserved nature and expression in various tissues of the human body make it a promising candidate for small molecule inhibitors. Further research is needed to determine its role in the development and progression of various diseases.

Protein Name: Oxysterol Binding Protein Like 11

Functions: Plays a role in regulating ADIPOQ and FABP4 levels in differentiating adipocytes and is also involved in regulation of adipocyte triglyceride storage (PubMed:23028956). Weakly binds 25-hydroxycholesterol (PubMed:17428193)

The "OSBPL11 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about OSBPL11 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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