ANTIPARKOVSKY1: Potential Therapeutic and Research Target (G51479)

Target Name: ANKFY1

NCBI ID: G51479

ANKFY1

ANTIPARKOVSKY1: Potential Therapeutic and Research Target

ANKFY1 (KIAA1255) is a protein that is expressed in a variety of tissues throughout the body, including the brain. It is a member of the KIAA family of proteins, which are known as the K-type ATP-binding proteins. These proteins are Involved in a variety of cellular processes, including signaling, muscle contractions, and cell survival.

One of the unique features of ANKFY1 is its ability to interact with the protein p110R, which is a cofactor of the protein kinase AAF/PKG. This interaction allows ANKFY1 to participate in a variety of cellular processes, including the regulation of ion channels, neurotransmitter signaling, and cell survival.

ACKFY1 has also been shown to play a role in the regulation of cell adhesion. It is a member of the cadherin family of transmembrane proteins, which are involved in the formation of tight junctions and tight-packed packets that mediate the transfer of matter across the cell membrane.

In addition to its role in cell signaling and cell adhesion, ANKFY1 has also been shown to be involved in the regulation of cellular processes that are important for brain development and function. For example, it has been shown to play a role in the regulation of neuron migration, synaptic formation, and neurotransmitter release.

Given its unique combination of functions, ANKFY1 has potential as a drug target or biomarker. For example, it could be used to treat a variety of neurological and psychiatric disorders, including Alzheimer's disease, Parkinson's disease, and depression.

In addition to its potential therapeutic applications, ANKFY1 also has potential as a research tool. Researchers have been able to use techniques such as RNA interference and protein arrays to study the effects of various molecules on the expression and activity of ANKFY1. This has allowed them to gain a better understanding of the mechanisms that ANKFY1 is involved in.

Overall, ANKFY1 is a protein that has the potential to be a drug target or biomarker, and further research is needed to fully understand its functions and mechanisms.

Protein Name: Ankyrin Repeat And FYVE Domain Containing 1

Functions: Proposed effector of Rab5. Binds to phosphatidylinositol 3-phosphate (PI(3)P). Involved in homotypic early endosome fusion and to a lesser extent in heterotypic fusion of chlathrin-coated vesicles with early endosomes. Involved in macropinocytosis; the function is dependent on Rab5-GTP. Required for correct endosomal localization. Involved in the internalization and trafficking of activated tyrosine kinase receptors such as PDGFRB. Regulates the subcellular localization of the retromer complex in a EHD1-dependent manner. Involved in endosome-to-Golgi transport and biosynthetic transport to late endosomes and lysosomes indicative for a regulation of retromer complex-mediated retrograde transport

The "ANKFY1 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about ANKFY1 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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