S100A7A: A Protein Involved in Cell Signaling and Disease Development

Target Name: S100A7A

NCBI ID: G338324

S100A7A

S100A7A: A Protein Involved in Cell Signaling and Disease Development

S100A7A, also known as S100A7f, is a protein that is expressed in various tissues throughout the body. It is a member of the S100 family of proteins, which are known for their role in cell signaling and cytoskeletal organization. S100A7A is unique among its family members because of its unique expression pattern and its role in the development and progression of various diseases.

The S100 family of proteins was first identified in the 1970s based on its ability to interact with the protein S100A6. S100A6 is a nuclear protein that is involved in the regulation of cell growth, differentiation, and adhesion. The S100 family has since been identified in a wide variety of organisms, including humans.

S100A7A is a 19-kDa protein that is expressed in various tissues, including brain, heart, liver, and muscle. It is primarily localized to the cytoplasm of cells and is involved in the regulation of cell adhesion, migration, and invasion. S100A7A is also involved in the regulation of cellular signaling pathways, including the TGF-β pathway.

One of the unique features of S100A7A is its ability to interact with the protein TGF-β2. TGF-β2 is a cytokine that plays a critical role in the regulation of cellular growth, differentiation, and survival. It is expressed in various tissues throughout the body and is involved in the development and progression of many diseases, including cancer.

S100A7A has been shown to play a critical role in the regulation of TGF-β2 signaling in various tissues. For example, studies have shown that S100A7A can interact with TGF-β2 and regulate its activity. This interaction between S100A7A and TGF-β2 has important implications for the regulation of cellular processes that are involved in disease development.

In addition to its role in TGF-β2 signaling, S100A7A has also been shown to be involved in the regulation of other signaling pathways, including the PI3K/Akt signaling pathway. This pathway is involved in the regulation of cellular signaling pathways that are involved in cell survival and growth, and is a potential target for the development of new therapeutic strategies for a variety of diseases.

S100A7A has also been shown to be involved in the regulation of cellular apoptosis, which is the process by which cells undergo programmed cell death. Apoptosis is a natural process that is involved in the regulation of cellular life and death, and is important for the development and progression of diseases.

S100A7A has been shown to play a critical role in the regulation of apoptosis in various tissues. For example, studies have shown that S100A7A can interact with the protein Bcl-2 and regulate its activity. Bcl-2 is a protein that is involved in the regulation of apoptosis, and its activity is regulated by S100A7A. This interaction between S100A7A and Bcl-2 has important implications for the regulation of apoptosis and the potential development of new therapeutic strategies for diseases.

In conclusion, S100A7A is a protein that is involved in the regulation of various cellular processes that are involved in disease development. Its unique expression pattern and its role in the regulation of TGF-β2 and other signaling pathways make it a potential drug target or biomarker for a variety of diseases. Further research is needed to fully understand the role of S100A7A in disease development and the development of new therapeutic strategies.

Protein Name: S100 Calcium Binding Protein A7A

Functions: May be involved in epidermal differentiation and inflammation and might therefore be important for the pathogenesis of psoriasis and other diseases

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•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
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•   the target screening and validation;
•   expression level;
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•   related combination drugs;
•   pharmacochemistry experiments;
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•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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