RAB4B: A Drug Target / Disease Biomarker (G53916)

Target Name: RAB4B

NCBI ID: G53916

RAB4B

RAB4B: A Drug Target / Disease Biomarker

RAB4B is a protein that is expressed in various tissues throughout the body, including the brain, pancreas, and gastrointestinal tract. It is a member of the Rab gene family, which is known for the production of small GTPases, which are a type of protein that plays a critical role in cell signaling.

One of the functions of RAB4B is to regulate the activity of these GTPases. This is accomplished through a process called GTPase-activating protein (GAP) function, which involves the formation of a protein-protein interaction between RAB4B and a GAP. Once this interaction is established, RAB4B can activate the GTPase activity of its associated GAP, leading to the production of various downstream signaling molecules.

One of the unique features of RAB4B is its ability to form multiple interactions with different GAPs, allowing it to regulate the activity of a wide range of GTPases. This makes it an attractive target for the development of new drugs that can modulate GTPase activity and treat a variety of diseases.

In addition to its role in GTPase regulation, RAB4B is also involved in the regulation of various cellular processes that are important for maintaining cellular homeostasis. For example, it is involved in the production of the peptidoglycan molecule, which is a key component of the cell's cytoskeleton and helps to maintain the structural integrity of the cell.

RAB4B is also involved in the regulation of the actinin protein, which is involved in the movement of cells and is essential for the proper functioning of many cellular processes. In addition, RAB4B is involved in the regulation of the protein kinase B3 (PKB), which is involved in the production of various signaling molecules that are important for cellular growth and development.

Despite its many functions, RAB4B is still an relatively unexplored protein. There is currently limited research on the mechanisms of its regulation and the role it plays in various cellular processes. This lack of understanding makes it an attractive target for the development of new drugs that can modulate its activity and treat a variety of diseases.

In conclusion, RAB4B is a protein that is expressed in various tissues throughout the body and is involved in the regulation of various cellular processes that are important for maintaining cellular homeostasis. Its unique ability to form multiple interactions with different GAPs makes it an attractive target for the development of new drugs that can modulate its activity and treat a variety of diseases. Further research is needed to fully understand the mechanisms of RAB4B's regulation and its role in cellular processes.

Protein Name: RAB4B, Member RAS Oncogene Family

Functions: Small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state (By similarity). Protein transport. Probably involved in vesicular traffic (By similarity). Acts as a regulator of platelet alpha-granule release during activation and aggregation of platelets (By similarity)

The "RAB4B Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about RAB4B comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets