Target Name: SMOX
NCBI ID: G54498
Review Report on SMOX Target / Biomarker Content of Review Report on SMOX Target / Biomarker
SMOX
Other Name(s): SMOX variant 1 | SMOX variant 6 | flavin containing amine oxidase | PAOH1 | Spermine oxidase (isoform 6) | Putative cyclin G1 interacting protein | Spermine oxidase (isoform 2) | PAOh1/SMO | putative cyclin G1 interacting protein | PAO1 | flavin-containing spermine oxidase | Polyamine oxidase 1 | SMO5 | Spermine oxidase, transcript variant 4 | SMOX variant 2 | PAOh1 | spermine oxidase | SMOX_HUMAN | SMO/PAOh1 | Spermine oxidase | C20orf16 | PAO | Spermine oxidase, transcript variant 6 | MGC1010 | polyamine oxidase 1 | Spermine oxidase, transcript variant 1 | SMOX variant 4 | FLJ20746 | PAO-1 | SMO(PAOh1) | Spermine oxidase, transcript variant 2 | Flavin containing amine oxidase | Spermine oxidase (isoform 4) | PAOh1 (ambiguous) | Flavin-containing spermine oxidase | PAOH | SMO | Spermine oxidase (isoform 1)

SMOX: A Drug Target / Disease Biomarker

SMOX is a protein that is expressed in various tissues throughout the body, including the brain, lungs, heart, and kidneys. It is a key regulator of the cell cycle, which means it helps keep cells organized and growing.

SMOX has also been shown to play a role in a variety of diseases, including cancer, neurodegenerative diseases, and respiratory disorders. It has been identified as a potential drug target for several of these conditions, and research is ongoing to determine its effectiveness as a treatment.

One of the ways that SMOX is being studied as a drug target is its ability to inhibit the growth and spread of cancer cells. Studies have shown that SMOX can cause cancer cells to stop dividing and undergo apoptosis, which is a natural form of cell death. This can be a powerful way to treat cancer, as it allows doctors to target the cells that are most dangerous and destroy them without causing harm to healthy cells.

Another way that SMOX is being studied as a drug target is its ability to treat neurodegenerative diseases. These conditions include Alzheimer's disease, Parkinson's disease, and Huntington's disease, and they are characterized by the progressive loss of brain cells. SMOX has been shown to improve the cognitive function and reduce the number of neurofibrillary tangles in individuals with these conditions.

SMOX is also being studied as a potential treatment for respiratory disorders. Chronic obstructive pulmonary disease (COPD) is a common respiratory disorder that is characterized by difficulty breathing and coughing, and it is a leading cause of death in the United States. SMOX has been shown to improve lung function and reduce inflammation in individuals with COPD.

In addition to its potential as a drug target, SMOX is also being studied for its potential role in the development and progression of various diseases. For example, studies have shown that high levels of SMOX are associated with an increased risk of developing heart disease and kidney disease.

Overall, SMOX is a protein that is being studied as a potential drug target for a variety of conditions. Its ability to inhibit cell division and promote apoptosis makes it a promising target for cancer, neurodegenerative diseases, and respiratory disorders. Further research is needed to determine its effectiveness as a treatment and to develop it into a safe and effective drug.

Protein Name: Spermine Oxidase

Functions: Flavoenzyme which catalyzes the oxidation of spermine to spermidine. Can also use N(1)-acetylspermine and spermidine as substrates, with different affinity depending on the isoform (isozyme) and on the experimental conditions. Plays an important role in the regulation of polyamine intracellular concentration and has the potential to act as a determinant of cellular sensitivity to the antitumor polyamine analogs. May contribute to beta-alanine production via aldehyde dehydrogenase conversion of 3-amino-propanal

The "SMOX Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about SMOX comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets

SMPD1 | SMPD2 | SMPD3 | SMPD4 | SMPD4BP | SMPD4P1 | SMPD5 | SMPDL3A | SMPDL3B | SMPX | SMR3A | SMR3B | SMS | SMTN | SMTNL1 | SMTNL2 | SMU1 | SMUG1 | SMURF1 | SMURF2 | SMURF2P1-LRRC37BP1 | SMYD1 | SMYD2 | SMYD3 | SMYD4 | SMYD5 | SNAI1 | SNAI2 | SNAI3 | SNAI3-AS1 | SNAP23 | SNAP25 | SNAP25-AS1 | SNAP29 | SNAP47 | SNAP91 | SNAPc complex | SNAPC1 | SNAPC2 | SNAPC3 | SNAPC4 | SNAPC5 | SNAPIN | SNAR-A1 | SNAR-A2 | SNAR-A3 | SNAR-B1 | SNAR-B2 | SNAR-C1 | SNAR-C3 | SNAR-D | SNAR-E | SNAR-G2 | SNAR-H | SNAR-I | SNARE complex | SNARP complex | SNCA | SNCA-AS1 | SNCAIP | SNCB | SNCG | SND1 | SND1-IT1 | SNED1 | SNF8 | SNF8P1 | SNHG1 | SNHG10 | SNHG11 | SNHG12 | SNHG14 | SNHG15 | SNHG16 | SNHG17 | SNHG18 | SNHG19 | SNHG20 | SNHG22 | SNHG25 | SNHG29 | SNHG3 | SNHG31 | SNHG32 | SNHG4 | SNHG5 | SNHG6 | SNHG7 | SNHG8 | SNHG9 | SNIP1 | SNN | SNORA1 | SNORA10 | SNORA10B | SNORA11 | SNORA11B | SNORA11E | SNORA12 | SNORA13