Target Name: DIRAS2
NCBI ID: G54769
Review Report on DIRAS2 Target / Biomarker Content of Review Report on DIRAS2 Target / Biomarker
DIRAS2
Other Name(s): DIRA2_HUMAN | DIRAS family GTPase 2 | Di-Ras2 | DIRAS family, GTP-binding RAS-like 2 | GTP-binding protein Di-Ras2 | Distinct subgroup of the Ras family member 2 | distinct subgroup of the Ras family member 2 | DKFZp761C07121

DIRAS2: A Promising Drug Target / Biomarker

DIRAS2 is a protein that is expressed in various tissues throughout the body. It is a member of the insulin-like growth factor (IGF) family and has been shown to play a role in several biological processes, including cell growth, differentiation, and survival. While the exact function of DIRAS2 is not yet fully understood, it is clear that it is a promising drug target and potential biomarker for several diseases. In this article, we will explore the biology of DIRAS2 and its potential as a drug target.

The Biology of DIRAS2

DIRAS2 is a 21-kDa protein that is expressed in a variety of tissues, including muscle, bone, heart, and brain. It is a member of the insulin-like growth factor (IGF) family, which is a group of proteins that are involved in cell growth, differentiation, and survival. The IGF family includes several different proteins, including IGF-1, IGF-2, IGF-3, and IGF-5. These proteins all share a common catalytic domain and a similar structure, but they differ in their length and/or function.

DIRAS2 is involved in several important biological processes, including cell growth, differentiation, and survival. It has been shown to play a role in the regulation of cell proliferation, cell differentiation, and cell survival. For example, DIRAS2 has been shown to promote the growth and survival of cancer cells (3), and it has also been shown to play a role in the regulation of cell differentiation, with DIRAS2+ cells showing more stem-like properties.

In addition to its role in cell biology, DIRAS2 has also been shown to play a role in the regulation of inflammation. DIRAS2 has been shown to regulate the production of pro-inflammatory cytokines, such as TNF-alpha and IL-8, and has been shown to protect against the effects of these cytokines.

Potential Therapeutic Applications

DIRAS2 has the potential to be a drug target for several diseases due to its involvement in several important biological processes. As a drug target, DIRAS2 could be used to treat a variety of diseases, including cancer, neurodegenerative diseases, and autoimmune diseases.

For example, DIRAS2 has been shown to be involved in the regulation of cancer cell growth and survival, which makes it a potential target for cancer therapies. DIRAS2 has also been shown to play a role in the regulation of neurodegenerative diseases, such as Alzheimer's disease and Parkinson's disease, which makes it a potential target for these therapies. In addition, DIRAS2 has been shown to be involved in the regulation of autoimmune diseases, such as rheumatoid arthritis and multiple sclerosis, which makes it a potential target for these therapies as well.

DIRAS2 has also been shown to be a potential biomarker for several diseases. For example, DIRAS2 has been shown to be elevated in the blood of patients with cancer, and has been used as a biomarker for cancer diagnosis and treatment. In addition, DIRAS2 has also been shown to be elevated in the brains of patients with neurodegenerative diseases, such as Alzheimer's disease and Parkinson's disease, which could be used as a biomarker for these diseases as well.

Conclusion

DIRAS2 is a protein that is expressed in various tissues throughout the body and is involved in several important biological processes, including cell growth, differentiation, and survival. While the exact function of DIRAS2 is not yet fully understood, it is clear that it is a promising drug target and potential biomarker for several diseases. Further research is needed to fully understand the role of DIRAS2 in biology and to develop effective therapies based on it.

Protein Name: DIRAS Family GTPase 2

Functions: Displays low GTPase activity and exists predominantly in the GTP-bound form

The "DIRAS2 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about DIRAS2 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets

DIRAS3 | DIRC1 | DIRC3 | DIRC3-AS1 | DIS3 | DIS3L | DIS3L2 | DISC1 | DISC1FP1 | DISC2 | Disintegrin and Metalloproteinase domain-containing protein (ADAM) (nospecified subtype) | DISP1 | DISP2 | DISP3 | DIXDC1 | DKC1 | DKFZp434L192 | DKFZp451A211 | DKFZp451B082 | DKFZP586I1420 | DKK1 | DKK2 | DKK3 | DKK4 | DKKL1 | DLAT | DLC1 | DLD | DLEC1 | DLEU1 | DLEU2 | DLEU2L | DLEU7 | DLEU7-AS1 | DLG1 | DLG1-AS1 | DLG2 | DLG3 | DLG3-AS1 | DLG4 | DLG5 | DLG5-AS1 | DLGAP1 | DLGAP1-AS1 | DLGAP1-AS2 | DLGAP1-AS5 | DLGAP2 | DLGAP3 | DLGAP4 | DLGAP5 | DLK1 | DLK2 | DLL1 | DLL3 | DLL4 | DLST | DLSTP1 | DLX1 | DLX2 | DLX2-DT | DLX3 | DLX4 | DLX5 | DLX6 | DLX6-AS1 | DM1-AS | DMAC1 | DMAC2 | DMAC2L | DMAP1 | DMBT1 | DMBT1L1 | DMBX1 | DMC1 | DMD | DMGDH | DMKN | DMP1 | DMPK | DMRT1 | DMRT2 | DMRT3 | DMRTA1 | DMRTA2 | DMRTB1 | DMRTC1 | DMRTC1B | DMRTC2 | DMTF1 | DMTF1-AS1 | DMTN | DMWD | DMXL1 | DMXL2 | DNA ligase | DNA Methyltransferase (DNMT) | DNA Polymerase alpha | DNA polymerase delta | DNA Polymerase epsilon | DNA Polymerase gamma