Target Name: MS4A12
NCBI ID: G54860
Review Report on MS4A12 Target / Biomarker Content of Review Report on MS4A12 Target / Biomarker
MS4A12
Other Name(s): membrane spanning 4-domains A12 | Membrane-spanning 4-domains subfamily A member 12 | OTTHUMP00000229465 | Membrane spanning 4-domains A12, transcript variant 1 | Membrane-spanning 4-domains subfamily A member 12 (isoform 1) | Ms4a10 | MS4A12 variant 1 | M4A12_HUMAN | OTTHUMP00000229466

MS4A12: A Protein Regulator of Cell Signaling, Adhesion and Inflammation

MS4A12, also known as membrane spanning 4-domain A12, is a protein that is expressed in various tissues throughout the body. It plays a crucial role in the structure and function of many different cell types, including neurons, muscle cells, and immune cells.

One of the most significant functions of MS4A12 is its role in cell signaling. It is a key regulator of the protein kinase CKL, which is involved in a wide range of cellular processes, including cell growth, differentiation, and survival. MS4A12 has been shown to interact with CKL and regulate its activity, which has important implications for the regulation of cellular processes that are critical for human health and disease.

Another important function of MS4A12 is its role in cell adhesion. MS4A12 is involved in the formation of tight junctions, which are critical for the proper functioning of cells in the body. These connections help to maintain the integrity of tissues and are involved in various physiological processes, including the regulation of ion and solute transport and the development of cancer.

MS4A12 is also involved in the regulation of inflammation. It has been shown to play a key role in the regulation of the immune response, particularly in the regulation of T cell activity. MS4A12 has been shown to interact with the immune protein PD-L1 and regulate its activity, which has important implications for the regulation of autoimmune diseases.

In addition to its role in cell signaling and adhesion, MS4A12 is also involved in the regulation of cell death. It has been shown to play a key role in the regulation of apoptosis, which is a natural process that helps to remove damaged or dysfunctional cells from the body. MS4A12 has been shown to interact with the protein Bcl-2 and regulate its activity, which has important implications for the regulation of cellular processes that are critical for human health and disease.

MS4A12 is also of interest as a potential drug target. Its role in the regulation of cell signaling, adhesion, inflammation, and cell death makes it a potential target for small molecules that can modulate these processes. This has led to a growing interest in the development of compounds that can inhibit or enhance the activity of MS4A12, with the goal of treating a wide range of diseases.

In conclusion, MS4A12 is a protein that is involved in a wide range of cellular processes that are critical for human health and disease. Its role in cell signaling, adhesion, inflammation, and cell death makes it a potential drug target, with potential therapeutic applications in a wide range of diseases. Further research is needed to fully understand the mechanisms of MS4A12 and its role in cellular processes, and to develop compounds that can modulate its activity.

Protein Name: Membrane Spanning 4-domains A12

Functions: May be involved in signal transduction as a component of a multimeric receptor complex

The "MS4A12 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about MS4A12 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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