MS4A8: A Membrane-spanning 4-Domains Subfamily A Member 8 Drug Target and Biomarker

Target Name: MS4A8

NCBI ID: G83661

MS4A8

MS4A8: A Membrane-spanning 4-Domains Subfamily A Member 8 Drug Target and Biomarker

Membrane-spanning 4-domains (MS4A) are a family of proteins that play a crucial role in various cellular processes. MS4A8, a member of the MS4A subfamily, is a protein that has been identified as a potential drug target and biomarker for various diseases, including cancer, neurodegenerative diseases, and autoimmune disorders.

The MS4A8 Protein

MS4A8 is a 194-kDa protein that is expressed in various tissues, including brain, heart, liver, and pancreas. It is localized to the endoplasmic reticulum (ER) and has been shown to be involved in the regulation of cellular processes such as cell adhesion, migration, and signaling pathways.

In addition to its cytoskeletal functions, MS4A8 has also been shown to play a role in the regulation of ion channels, which are critical for the proper functioning of various cellular processes. Specifically, MS4A8 has been shown to interact with Na+ channels, which are involved in neurotransmitter signaling and contribute to the regulation of pain perception, anxiety, and other physiological processes.

Drug Target Potential

The drug targeting potential of MS4A8 is high due to its various functions in cellular processes. One of the primary drug targets for MS4A8 is the regulation of ion channels, which can be manipulated by small molecules such as drugs. For example, inhibitors of Na+ channels have been shown to have therapeutic potential for various neurological and psychiatric disorders, including Alzheimer's disease, Parkinson's disease, and epilepsy.

In addition to its potential as a drug target, MS4A8 has also been shown to be a potential biomarker for various diseases. The regulation of ion channels is involved in the regulation of various physiological processes, including the regulation of pain perception, which is often associated with MS4A8-related diseases.

Biomarker Potential

The MS4A8 protein has been shown to be involved in the regulation of various physiological processes, including pain perception, which is often associated with MS4A8-related diseases. Therefore, MS4A8 has great potential as a biomarker for various diseases.

One of the primary applications of MS4A8 as a biomarker is its ability to serve as a therapeutic target for pain perception. Pain perception is often associated with various neurological and psychiatric disorders, including chronic pain, neurodegenerative diseases, and psychiatric disorders. Therefore, targeting MS4A8 with small molecules or other therapeutic approaches may provide relief from pain in these disorders.

Another application of MS4A8 as a biomarker is its involvement in the regulation of neurotransmitter signaling pathways. MS4A8 has been shown to interact with various neurotransmitter receptors, including dopamine, serotonin, and GABA. Therefore, alterations in MS4A8 expression levels or function may be involved in the regulation of neurotransmitter signaling pathways.

Conclusion

In conclusion, MS4A8 is a protein that has been identified as a potential drug target and biomarker for various diseases. Its functions in the regulation of cellular processes, including cell adhesion, migration, and signaling pathways, as well as its involvement in the regulation of ion channels and neurotransmitter signaling pathways make it an attractive target for small molecules and other therapeutic approaches. Further research is needed to fully understand the potential of MS4A8 as a drug target and biomarker for various diseases.

Protein Name: Membrane Spanning 4-domains A8

Functions: May be involved in signal transduction as a component of a multimeric receptor complex

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•   general information;
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•   the target screening and validation;
•   expression level;
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The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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