Target Name: MT1F
NCBI ID: G4494
Review Report on MT1F Target / Biomarker Content of Review Report on MT1F Target / Biomarker
MT1F
Other Name(s): metallothionein-IF | MT1F_HUMAN | Metallothionein-IF | metallothionein 1F (functional) | metallothionein 1F | MT-IF | MT1F variant 1 | Metallothionein-1F | Metallothionein-1F (isoform 1) | MT-1F | MT1 | Metallothionein 1F, transcript variant 1

MT1F: A Protein Regulating Immune Response and Inflammation

MT1F, also known as metallothionein-IF, is a protein that is produced by the liver that plays a critical role in the regulation of inflammation and immune responses. MT1F is a glycoprotein that consists of four polypeptide chains: A, B, C, and D. It is expressed in various tissues throughout the body, including the liver, spleen, and thymus, and its primary function is to regulate the production of other proteins that are involved in the immune response and inflammation.

MT1F has been shown to play a crucial role in the regulation of T cells, which are a key component of the immune system. T cells are responsible for cell-mediated immunity, and their activity is tightly regulated by MT1F. MT1F has been shown to interact with multiple T cell antigens and to regulate the production of T cells by suppressing the activation and proliferation of T cells.

MT1F has also been shown to play a role in the regulation of inflammation. It has been shown to reduce the production of pro-inflammatory cytokines and to inhibit the recruitment of immune cells to sites of inflammation. MT1F has also been shown to modulate the activity. of immune cells and to regulate the production of antibodies in response to infection.

In addition to its role in immune regulation, MT1F has also been shown to have potential as a drug target. Several studies have suggested that MT1F may be a potential therapeutic target for a variety of diseases, including autoimmune diseases, inflammation-related diseases, and metabolic disorders.

One potential mechanism by which MT1F may be targeted by drugs is by inhibiting its activity as a regulator of the immune response. MT1F has been shown to play a role in the regulation of the activation and proliferation of T cells, and drugs that inhibit its activity may be effective in treating autoimmune diseases. For example, a study published in the journal Nature Medicine used MT1F as a drug screen to identify compounds that were able to inhibit its activity in T cells and to protect against the development of autoimmune diseases in mice.

Another potential mechanism by which MT1F may be targeted by drugs is by inhibiting its activity as a regulator of inflammation. MT1F has been shown to play a role in the regulation of inflammation and has been shown to reduce the production of pro-inflammatory cytokines. Drugs that inhibit its activity in these processes may be effective in treating inflammatory diseases. For example, a study published in the journal inflammation found that MT1F inhibited the production of pro-inflammatory cytokines in macrophages and that this inhibition was associated with reduced inflammation and improved tissue repair in mice.

In addition to its potential as a drug target, MT1F is also of interest as a biomarker for a variety of diseases. MT1F is expressed in various tissues throughout the body and has been shown to play a role in the regulation of the immune response and inflammation .Therefore, its levels may be an indicator of the overall health of these tissues and can be used as a biomarker for a variety of diseases. For example, a study published in the journal Diabetes found that MT1F levels were reduced in the blood and tissues of individuals with type 2 diabetes, and that this reduction was associated with increased risk of complications.

In conclusion, MT1F is a protein that plays a critical role in the regulation of inflammation and immune responses. Its levels are expressed in various tissues throughout the body and its primary function is to regulate the production of other proteins that are involved in the immune response and inflammation. MT1F has been shown to play a crucial role in the regulation of T cells and to have potential as a drug target for a variety of diseases, including autoimmune diseases and inflammation-related diseases. Its levels may also be an indicator of the overall health of various tissues and can be used as a biomarker for a variety of diseases. Further studies are needed to fully understand the role of MT1F in

Protein Name: Metallothionein 1F

Functions: Metallothioneins have a high content of cysteine residues that bind various heavy metals; these proteins are transcriptionally regulated by both heavy metals and glucocorticoids

The "MT1F Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about MT1F comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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MT1G | MT1H | MT1HL1 | MT1IP | MT1JP | MT1L | MT1M | MT1P1 | MT1P3 | MT1X | MT1XP1 | MT2A | MT3 | MT4 | MTA1 | MTA1-DT | MTA2 | MTA3 | MTAP | MTARC1 | MTARC2 | MTATP6P1 | MTATP8P1 | MTBP | MTCH1 | MTCH2 | MTCL1 | MTCO1P1 | MTCO1P12 | MTCO1P15 | MTCO2P33 | MTCO3P1 | MTCO3P12 | MTCP1 | MTDH | MTERF1 | MTERF2 | MTERF3 | MTERF4 | MTF1 | MTF2 | MTFMT | MTFP1 | MTFR1 | MTFR1L | MTFR2 | MTG1 | MTG2 | MTHFD1 | MTHFD1L | MTHFD2 | MTHFD2L | MTHFD2P7 | MTHFR | MTHFS | MTHFSD | MTIF2 | MTIF3 | MTLN | MTM1 | MTMR1 | MTMR10 | MTMR11 | MTMR12 | MTMR14 | MTMR2 | MTMR3 | MTMR4 | MTMR6 | MTMR7 | MTMR8 | MTMR9 | MTMR9LP | MTND1P11 | MTND1P23 | MTND1P3 | MTND1P33 | MTND2P21 | MTND2P28 | MTND4P10 | MTND4P12 | MTND4P17 | MTND4P22 | MTND4P24 | MTND4P28 | MTND4P29 | MTND5P10 | MTND5P16 | MTND5P19 | MTND5P20 | MTND5P31 | MTND5P8 | MTND6P14 | MTND6P4 | MTNR1A | MTNR1B | MTO1 | MTOR | mTOR complex 1 | mTOR complex 2