MTA2: A Potential Drug Target and Biomarker for Cancer (G9219)

Target Name: MTA2

NCBI ID: G9219

MTA2

MTA2: A Potential Drug Target and Biomarker for Cancer

Metastasis-associated protein MTA2 (isoform 1) is a protein that is expressed in various tissues and cells throughout the body. It plays a crucial role in the regulation of cell growth, apoptosis, and metastasis. MTA2 is also a potential drug target and biomarker for various diseases, including cancer.

MTA2 was first identified in the late 1990s as a protein that was expressed in various tissues, including the brain, lung, heart, and gastrointestinal tract. It is also found in the bloodstream and has been shown to play a role in the regulation of cellular processes, including cell adhesion, migration, and invasion.

One of the most significant functions of MTA2 is its role in cell apoptosis. Apoptosis is a natural process that helps the body remove damaged or dysfunctional cells. MTA2 is involved in the regulation of apoptosis by activating and inhibiting various apoptosis-related genes.

MTA2 has also been shown to play a role in the regulation of cell growth and proliferation. It has been shown to inhibit the growth and proliferation of various cancer cell lines, including breast, lung, and ovarian cancer cells.

In addition to its role in cell regulation, MTA2 has also been shown to be involved in the development and progression of various diseases, including cancer. For example, studies have shown that MTA2 is overexpressed in various types of cancer, including breast, lung, and ovarian cancer. This suggests that MTA2 may be a useful biomarker for these diseases and may also be a potential drug target.

MTA2 has also been shown to be involved in the regulation of the immune response. It has been shown to modulate the activity of T cells, which play a crucial role in the immune response.

In conclusion, MTA2 is a protein that plays a crucial role in the regulation of cell growth, apoptosis, and metastasis. It is also a potential drug target and biomarker for various diseases, including cancer. Further research is needed to fully understand the functions of MTA2 and its potential as a drug.

Protein Name: Metastasis Associated 1 Family Member 2

Functions: May function as a transcriptional coregulator (PubMed:16428440, PubMed:28977666). Acts as a component of the histone deacetylase NuRD complex which participates in the remodeling of chromatin (PubMed:16428440, PubMed:28977666)

The "MTA2 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about MTA2 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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