SEMA4C: A Protein Targeted for Cancer, Neurodegenerative Diseases and Autoimmune Disorders

Target Name: SEMA4C

NCBI ID: G54910

SEMA4C

SEMA4C: A Protein Targeted for Cancer, Neurodegenerative Diseases and Autoimmune Disorders

SEMA4C is a protein that is expressed in various tissues throughout the body, including the brain, lungs, heart, and kidneys. It is a member of the Smin family, which includes proteins that are involved in various cellular processes, including cell signaling and organization.

SEMA4C has been identified as a potential drug target (or biomarker) due to its involvement in several disease processes, including cancer, neurodegenerative diseases, and autoimmune disorders.

One of the key functions of SEMA4C is its role in cell signaling. It is involved in the regulation of cell proliferation, differentiation, and survival, and is thought to play a key role in the development and progression of cancer.

SEMA4C has also been linked to several neurodegenerative diseases, including Alzheimer's disease and Parkinson's disease. These conditions are characterized by the progressive loss of brain cells, and are associated with a range of symptoms, including cognitive decline, tremors, and difficulty with movement.

SEMA4C is also involved in the regulation of immune responses, which is important for maintaining the immune system's ability to fight off infections and diseases. Imbalances in the immune system, such as those that occur in autoimmune disorders, can lead to the development of diseases such as rheumatoid arthritis and multiple sclerosis.

In addition to its role in cell signaling and immune function, SEMA4C is also thought to play a key role in the regulation of inflammation. Chronic inflammation, such as that which occurs in rheumatoid arthritis and other autoimmune disorders, can lead to the development of diseases that involve inflammation throughout the body.

Given its involvement in so many different cellular processes, SEMA4C is a promising target for drug development. Researchers are currently working to identify small molecules that can specifically interact with SEMA4C and modulate its activity. These molecules are being tested for their potential to treat a range of diseases, including cancer, neurodegenerative diseases, and autoimmune disorders.

While the development of SEMA4C as a drug target is still in its early stages, it is clear that it has the potential to be a valuable tool for the treatment of a wide range of diseases. Further research is needed to fully understand the mechanisms of SEMA4C's function and its potential as a drug target.

Protein Name: Semaphorin 4C

Functions: Cell surface receptor for PLXNB2 that plays an important role in cell-cell signaling. PLXNB2 binding promotes downstream activation of RHOA and phosphorylation of ERBB2 at 'Tyr-1248'. Required for normal brain development, axon guidance and cell migration (By similarity). Probable signaling receptor which may play a role in myogenic differentiation through activation of the stress-activated MAPK cascade

The "SEMA4C Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about SEMA4C comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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