Target Name: PROC
NCBI ID: G5624
Review Report on PROC Target / Biomarker Content of Review Report on PROC Target / Biomarker
PROC
Other Name(s): type I protein C | Autoprothrombin IIA | PROC1 | Vitamin K-dependent protein C light chain | Activated protein C | APC | Anticoagulant protein C | Activated blood coagulation factor XIV | THPH3 | coagulation factor XIV | protein C, inactivator of coagulation factors Va and VIIIa | Vitamin K-dependent protein C | Protein Ca | PC | Vitamin K-dependent protein C (isoform 10) | Autoprothrombin II-A | Activation peptide | Inactivator of coagulation factors Va and VIIIa | PROC_HUMAN | 3448141 | blood coagulation factor XIV | prepro-protein C | Blood coagulation factor XIV | anticoagulant protein C | Protein C, inactivator of coagulation factors Va and VIIIa, transcript variant 10 | activated protein C | autoprothrombin IIA | THPH4 | Vitamin K-dependent protein C heavy chain | PROC variant 10 | Blood-coagulation factor XIVa | Protein C-Nagoya

PROC: Key Player in Protein Synthesis and Degradation

PROC (Proteasome-Resetting Com protein) is a protein that is expressed in various tissues throughout the body. It is a key player in the regulation of protein synthesis and degradation, and is involved in the control of cell growth and differentiation. PROC is also a potential drug target and biomarker.

The protein encoded by the PROC gene is a 26 kDa protein that is composed of 196 amino acid residues. It has a molecular weight of 21.9 kDa and a calculated pI of 9.6. PROC is predominantly expressed in muscle, heart, and liver tissues, and is also found in the placenta and testes. It is a pro-survival protein, which means that it promotes the survival of cells under adverse conditions.

PROC plays a crucial role in the regulation of protein synthesis and degradation. It is involved in the formation of the 26 kDa protein complex, which is responsible for the degradation of damaged or unnecessary proteins. This process is critical for maintaining cellular homeostasis and for ensuring that the cell is able to respond quickly to changes in its environment.

PROC is also involved in the regulation of cell growth and differentiation. It has been shown to play a role in the regulation of cell proliferation, and is thought to be involved in the control of cell cycle progression. In addition, PROC is involved in the regulation of cell adhesion, and is thought to be involved in the development of tissues such as the brain and heart.

PROC is also a potential drug target and biomarker. Its involvement in the regulation of protein synthesis and degradation makes it an attractive target for the development of therapeutic agents that can modulate protein synthesis and degradation. In addition, its role in cell growth and differentiation makes it a potential biomarker for a variety of diseases, including cancer.

The regulation of protein synthesis and degradation is a complex process that is controlled by a variety of factors, including the availability of amino acids, the presence of nutrients, and the levels of various enzymes involved in the process. PROC is involved in the regulation of these factors, and is thought to play a key role in ensuring that cells are able to respond quickly and efficiently to changes in their environment.

In conclusion, PROC is a protein that is expressed in various tissues throughout the body and is involved in the regulation of protein synthesis and degradation. It is a potential drug target and biomarker, and its role in the regulation of cell growth and differentiation makes it an attractive target for the development of therapeutic agents. Further research is needed to fully understand the functions of PROC and its potential as a drug and biomarker.

Protein Name: Protein C, Inactivator Of Coagulation Factors Va And VIIIa

Functions: Protein C is a vitamin K-dependent serine protease that regulates blood coagulation by inactivating factors Va and VIIIa in the presence of calcium ions and phospholipids (PubMed:25618265). Exerts a protective effect on the endothelial cell barrier function (PubMed:25651845)

The "PROC Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about PROC comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets

PROCA1 | PROCR | PRODH | PRODHLP | Prohibitin | PROK1 | PROK2 | Prokineticin Receptor (PK-R) | PROKR1 | PROKR2 | Prolactin receptor (isoform 1) | Prolyl 4-hydroxylase | PROM1 | PROM2 | PROP1 | Propionyl-CoA Carboxylase | PRORP | PRORSD1P | PRORY | PROS1 | PROS2P | PROSER1 | PROSER2 | PROSER2-AS1 | PROSER3 | Prostaglandin EP Receptor | Prostaglandin synthase | Prostanoid Receptor | Prostanoid TP receptor | Proteasome 20S | Proteasome 26S | Proteasome Complex | Protein arginine N-methyltransferase | Protein disulfide-isomerase | Protein farnesyltransferase | Protein geranylgeranyltransferase type II | Protein kinase C | Protein Kinase D (PKD) | Protein kinase N | Protein NDRG2 (isoform a) | Protein Phosphatase | Protein Phosphatase 2A | Protein Phosphatase 2B | Protein phosphatase 6 | Protein phosphatase-1 | Protein transport protein Sec61 complex | Protein Tyrosine Phosphatase (PTP) | Protein Tyrosine Phosphatase Type IVA | Protein-Synthesizing GTPase (Elongation Factor) | Protocadherin | PROX1 | PROX1-AS1 | PROX2 | PROZ | PRPF18 | PRPF19 | PRPF3 | PRPF31 | PRPF38A | PRPF38B | PRPF39 | PRPF4 | PRPF40A | PRPF40B | PRPF4B | PRPF6 | PRPF8 | PRPH | PRPH2 | PRPS1 | PRPS1L1 | PRPS2 | PRPSAP1 | PRPSAP2 | PRR11 | PRR12 | PRR13 | PRR13P1 | PRR13P3 | PRR14 | PRR14L | PRR15 | PRR15L | PRR16 | PRR18 | PRR19 | PRR20B | PRR20C | PRR20D | PRR21 | PRR22 | PRR23A | PRR23B | PRR23C | PRR23D1 | PRR23E | PRR25 | PRR27 | PRR29 | PRR3