PROM1: Key Regulator of Cell Growth and Differentiation (G8842)

Target Name: PROM1

NCBI ID: G8842

PROM1

PROM1: Key Regulator of Cell Growth and Differentiation

PROM1 (Prominin 1) is a protein that is expressed in various tissues throughout the body, including the brain, pancreas, and gastrointestinal tract. It is a key regulator of cell growth and differentiation, and has been implicated in a number of diseases, including cancer, neurodegenerative diseases, and autoimmune disorders.

One of the key functions of PROM1 is its role in cell signaling. It is a protein that is involved in the F-actin signaling pathway, which is a critical pathway that regulates the movement of cells and cell processes. This pathway is important for many different functions in the body, including cell growth, differentiation, and response to stimuli.

Research has also suggested that PROM1 may have a role in the development and progression of certain diseases. For example, studies have shown that high levels of PROM1 are associated with poor prognosis in patients with pancreatic cancer, a particularly aggressive form of cancer. Additionally, animal models of neurodegenerative diseases, such as Alzheimer's disease, have shown that PROM1 is involved in the progression of these diseases.

Despite these promising findings, much more research is needed to fully understand the role of PROM1 in disease. One of the major challenges in studying PROM1 is its complex structure and the difficulty of studying a protein that is expressed in such a wide range of tissues. However, researchers are continuing to make progress and to develop new techniques for studying PROM1 and its role in disease.

In addition to its potential as a drug target or biomarker, PROM1 is also of interest to researchers because of its potential role in the development of certain diseases. For example, since PROM1 is involved in cell signaling, it is possible that it may be involved in the development of certain cancers, such as breast cancer. Additionally, since PROM1 is involved in the regulation of cell growth and differentiation, it is possible that it may be involved in the development of certain neurodegenerative diseases, such as Parkinson's disease.

Overall, PROM1 is a protein that is of great interest to researchers because of its role in cell signaling and its potential involvement in the development and progression of certain diseases. While more research is needed to fully understand its role, studies are continuing to make progress and to develop new techniques for studying PROM1 and its implications for disease.

Protein Name: Prominin 1

Functions: May play a role in cell differentiation, proliferation and apoptosis (PubMed:24556617). Binds cholesterol in cholesterol-containing plasma membrane microdomains and may play a role in the organization of the apical plasma membrane in epithelial cells. During early retinal development acts as a key regulator of disk morphogenesis. Involved in regulation of MAPK and Akt signaling pathways. In neuroblastoma cells suppresses cell differentiation such as neurite outgrowth in a RET-dependent manner (PubMed:20818439)

The "PROM1 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about PROM1 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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