PRORP: A Protein Potential Drug Target Or Biomarker (G9692)

Target Name: PRORP

NCBI ID: G9692

PRORP

PRORP: A Protein Potential Drug Target Or Biomarker

PRORP, or Mitochondrial Ribonuclease P Catalytic Subunit (ISOFORM 1), is a protein that is expressed in high levels in the mitochondria. It plays a critical role in the process of cell metabolism, and is a key enzyme in the mitochondrial ribonuclease complex, which is responsible for breaking down a variety of molecules, including fats and certain types of carbohydrates.

Recent studies have suggested that PRORP may be a drug target or biomarker for a variety of diseases, including cancer, cardiovascular disease, and neurological disorders. This is because of its involvement in the process of cell metabolism, which is often disrupted in these conditions. Additionally, its high expression levels in the mitochondria suggest that it may be a useful indicator of the level of cellular stress or dysfunction.

One potential mechanism by which PRORP could be targeted as a drug is its role in the process of cell metabolism. Many diseases, including cancer, are characterized by disruptions in the normal flow of energy through the cell. This can be caused by a variety of factors, including the presence of metabolic waste products or the absence of certain enzymes. PRORP is involved in breaking down these waste products and is thus a potential target for drugs that aim to inhibit the process of cell metabolism.

Another potential mechanism by which PRORP could be targeted is its role in the development of certain diseases. For example, PRORP has been shown to be highly expressed in the brains of individuals with Alzheimer's disease, a condition characterized by the progressive loss of brain cells. Additionally, PRORP has been shown to be involved in the production of reactive oxygen species, which can contribute to the development of certain diseases.

In addition to its potential as a drug target, PRORP also has potential as a biomarker. Its high expression levels in the mitochondria make it a useful indicator of cellular stress or dysfunction. This could make it a useful tool for the diagnosis and monitoring of certain diseases, such as those characterized by disruptions in cellular metabolism.

Overall, PRORP is a protein that is involved in a critical process in the cell. Its high expression levels in the mitochondria and its potential as a drug target or biomarker make it a promising target for the development of new therapies for a variety of diseases. Further research is needed to fully understand its role in the cell and its potential as a drug.

Protein Name: Protein Only RNase P Catalytic Subunit

Functions: Catalytic ribonuclease component of mitochondrial ribonuclease P, a complex composed of TRMT10C/MRPP1, HSD17B10/MRPP2 and PRORP/MRPP3, which cleaves tRNA molecules in their 5'-ends (PubMed:18984158, PubMed:25953853, PubMed:34715011). The presence of TRMT10C/MRPP1, HSD17B10/MRPP2 is required to catalyze tRNA molecules in their 5'-ends (PubMed:25953853)

The "PRORP Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about PRORP comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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