THAP11: A Protein Regulator of Cellular Processes and Diseases

Target Name: THAP11

NCBI ID: G57215

THAP11

THAP11: A Protein Regulator of Cellular Processes and Diseases

THAP11, also known as THAP11, is a protein that is expressed in various tissues of the body, including the brain, heart, and kidneys. It is a member of the TGF-β signaling pathway, which is a well-known regulatory pathway that plays a crucial role in the development and maintenance of various tissues and organs in the body.

THAP11 is a key regulator of the TGF-β pathway, and it is involved in the regulation of cell proliferation, differentiation, and survival. It is a transcription factor that can activate or repress the expression of target genes, and it has been shown to play a role in the regulation of a wide range of physiological processes, including brain development, neurogenesis, and tissue repair.

One of the key functions of THAP11 is its role in the regulation of neuronal stem cell proliferation and differentiation. THAP11 has been shown to play a key role in the regulation of neuronal stem cell proliferation by promoting the expression of genes that are involved in the maintenance of stem cell stemness.

In addition to its role in neuronal stem cell biology, THAP11 is also involved in the regulation of other cellular processes that are important for tissue development and repair. For example, it has been shown to play a role in the regulation of cell death, by promoting the expression of genes that are involved in cell apoptosis.

Thap11 is also involved in the regulation of inflammation, immune response and cell signaling. It has been shown to play a key role in the regulation of inflammation and immune response, by promoting the production of pro-inflammatory cytokines and the expression of immune checkpoints.

In addition to its role in inflammation and immune response, THAP11 is also involved in the regulation of cell signaling, by promoting the expression of genes that are involved in intracellular signaling pathways.

Due to its involvement in a wide range of physiological processes, THAP11 is a potential drug target or biomarker. Studies have shown that THAP11 has been involved in the regulation of a wide range of diseases and conditions, including cancer, neurodegenerative diseases, and autoimmune diseases.

In cancer, THAP11 has been shown to play a role in the regulation of cancer cell proliferation and survival. For example, studies have shown that high levels of THAP11 are associated with poor prognosis in breast cancer. Additionally, THAP11 has been shown to play a role in the regulation of the development and progression of colon cancer.

In neurodegenerative diseases, THAP11 has been shown to play a role in the regulation of neurogenesis and the maintenance of neural stem cells. For example, studies have shown that THAP11 is involved in the regulation of the production of new neurons in the brain, and that it plays a role in the maintenance of neural stem cells.

In autoimmune diseases, THAP11 has been shown to play a role in the regulation of immune response and inflammation. For example, studies have shown that THAP11 is involved in the regulation of the production of antibodies in the immune system, and that it plays a role in the regulation of the production of pro-inflammatory cytokines.

In conclusion, THAP11 is a protein that is involved in a wide range of physiological processes in the body, including cell proliferation, differentiation, and survival. It is a key regulator of the TGF-β pathway and has been shown to play a role in the regulation of a wide range of diseases and conditions, including cancer, neurodegenerative diseases, and autoimmune diseases. Therefore, THAP11 is a potential drug target or biomarker for future studies.

Protein Name: THAP Domain Containing 11

Functions: Transcriptional repressor that plays a central role for embryogenesis and the pluripotency of embryonic stem (ES) cells. Sequence-specific DNA-binding factor that represses gene expression in pluripotent ES cells by directly binding to key genetic loci and recruiting epigenetic modifiers (By similarity)

The "THAP11 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about THAP11 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
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•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
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•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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