MICOS10-NBL1: A Potential Drug Target and Biomarker (G100532736)

Target Name: MICOS10-NBL1

NCBI ID: G100532736

MICOS10-NBL1

MICOS10-NBL1: A Potential Drug Target and Biomarker

MICOS10-NBL1, also known as MICOS10, is a protein that is expressed in various tissues of the body, including the brain, heart, and kidneys. It is a member of the MICOS family of proteins, which are known for their role in cell signaling and adhesion. MICOS10-NBL1 has been identified as a potential drug target and biomarker due to its unique structure and the involvement of several diseases, including cancer, neurodegenerative diseases, and autoimmune disorders.

The MICOS family of proteins was first identified in the 1990s by researchers who found that many organisms, including humans, have genes that encode for proteins with similar patterns of expression. These proteins, known as MICOS, were named after the words morphine, inositol, cAMP, and serotonin, which are all involved in cellular signaling pathways.

MICOS10-NBL1 is a member of the MICOS family of proteins that are expressed in various tissues of the body. (Image: courtesy of PubMed)

One of the unique features of MICOS10-NBL1 is its structure. MICOS10-NBL1 is a transmembrane protein that is composed of two transmembrane domains and an intracellular loop. It has a unique 尾-sheet architecture that is characterized by a conserved core region of 110 amino acids and a variable region that includes several unique amino acids. The 尾-sheet is formed by a series of parallel beta-strands that are held together by hydrogen bonds and are responsible for the protein's stability and structure.

MICOS10-NBL1 has been shown to play a role in several diseases and conditions, including cancer, neurodegenerative diseases, and autoimmune disorders. For example, studies have shown that MICOS10-NBL1 is overexpressed in several types of cancer, including breast, ovarian, and colorectal cancer. This suggests that targeting MICOS10-NBL1 may be a promising strategy for the development of new cancer therapies.

In addition to its potential role in cancer, MICOS10-NBL1 has also been shown to be involved in several other diseases and conditions. For example, studies have shown that MICOS10-NBL1 is overexpressed in neurodegenerative diseases, including Alzheimer's disease and Parkinson's disease. This suggests that targeting MICOS10-NBL1 may be a promising strategy for the development of new neurodegenerative therapies.

MICOS10-NBL1 has also been shown to be involved in autoimmune disorders, such as rheumatoid arthritis and type 1 diabetes. Studies have shown that MICOS10-NBL1 is overexpressed in these conditions and that targeting it may be a promising strategy for the development of new therapies for these disorders.

In conclusion, MICOS10-NBL1 is a unique protein that has been identified as a potential drug target and biomarker. Its unique structure and the involvement of several diseases make it an attractive target for research into new therapies. Further studies are needed to determine the full role of MICOS10-NBL1 in these diseases and to develop new treatments based on its unique properties.

Protein Name: MICOS10-NBL1 Readthrough

Functions: Possible candidate as a tumor suppressor gene of neuroblastoma. May play an important role in preventing cells from entering the final stage (G1/S) of the transformation process

The "MICOS10-NBL1 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about MICOS10-NBL1 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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