SPOCK3: A Potential Drug Target and Biomarker (G50859)

Target Name: SPOCK3

NCBI ID: G50859

SPOCK3

SPOCK3: A Potential Drug Target and Biomarker

SPOCK3, short for short for spinal cord-associated protein 3, is a protein that is expressed in the spinal cord and is known for its role in the development and maintenance of spinal cord injuries. The spinal cord is a vital structure that carries nerve signals from the brain to the rest of the body. When it is damaged or impaired, it can result in a variety of neurological deficits, including weakness, pain, and loss of function.

SPOCK3 is a member of a family of proteins known as the SPOCK family, which are involved in various cellular processes, including cell signaling, DNA replication, and neurotransmitter release. The SPOCK family has been identified as a potential drug target in the development of spinal cord injuries.

SPOCK3 has been shown to be involved in the development of spinal cord injuries in both humans and animals. Studies have shown that SPOCK3 is expressed in the spinal cord and that its levels are decreased in individuals with spinal cord injuries. Additionally, experiments have shown that SPOCK3 interacts with other proteins involved in the development and progression of spinal cord injuries, including the neurotransmitter GABA.

SPOCK3 has also been shown to be involved in the regulation of pain. Studies have shown that SPOCK3 interacts with a protein called TRPV4, which is involved in the sensation of pain. Additionally, SPOCK3 has been shown to reduce the production of pain-related neurotransmitters in rats, suggesting that it may have potential as a pain therapeutic.

SPOCK3 may also have potential as a biomarker for spinal cord injuries. Studies have shown that SPOCK3 levels are decreased in individuals with spinal cord injuries, and that levels increase in response to therapeutic interventions. This suggests that SPOCK3 may be a useful biomarker for the diagnosis and assessment of spinal cord injuries.

In conclusion, SPOCK3 is a protein that has been shown to be involved in the development and maintenance of spinal cord injuries. Its levels are decreased in individuals with spinal cord injuries and have been shown to interact with other proteins involved in the development and progression of these injuries. Additionally, SPOCK3 has been shown to reduce the production of pain-related neurotransmitters in rats. These findings suggest that SPOCK3 may be a potential drug target and biomarker for the development of spinal cord injuries. Further research is needed to fully understand its role in this context.

Protein Name: SPARC (osteonectin), Cwcv And Kazal Like Domains Proteoglycan 3

Functions: May participate in diverse steps of neurogenesis. Inhibits the processing of pro-matrix metalloproteinase 2 (MMP-2) by MT1-MMP and MT3-MMP. May interfere with tumor invasion

The "SPOCK3 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about SPOCK3 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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