SPOPL: A Potential Drug Target for Cancer and Other Diseases (G339745)

Target Name: SPOPL

NCBI ID: G339745

SPOPL

SPOPL: A Potential Drug Target for Cancer and Other Diseases

SPOPL (Roadkill homolog 2) is a gene that has been identified as a potential drug target or biomarker for the treatment of various diseases, including cancer, neurodegenerative diseases, and autoimmune disorders. The gene is located on chromosome 1p36 and encodes a protein known as SPOPL, which is a key regulator of the growth and differentiation of neural cells.

SPOPL is a small molecule that is able to interact with several different proteins, including the oncogene PIK3CA. This interaction between SPOPL and PIK3CA has been shown to play a role in the development and progression of cancer. In addition, SPOPL has also been shown to interact with the neurotransmitter GABA, which is involved in a number of important cellular processes, including stress, anxiety, and learning.

SPOPL has also been shown to be involved in the regulation of cellular migration, which is a critical process for the development and progression of many diseases, including cancer. In addition, SPOPL has also been shown to be involved in the regulation of cell adhesion, which is important for the development and maintenance of tissues and organs.

SPOPL has also been shown to play a role in the regulation of the immune response, which is important for the fight against infection and disease. In addition, SPOPL has also been shown to be involved in the regulation of the production of proteins that are involved in cell signaling pathways, which is important for the development and progression of many diseases, including cancer.

In conclusion, SPOPL is a gene that has been identified as a potential drug target or biomarker for the treatment of a wide range of diseases. Further research is needed to fully understand the role of SPOPL in these diseases and to develop effective treatments.

Protein Name: Speckle Type BTB/POZ Protein Like

Functions: Component of a cullin-RING-based BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex that mediates the ubiquitination and subsequent proteasomal degradation of target proteins, but with relatively low efficiency. Cullin-RING-based BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complexes containing homodimeric SPOPL or the heterodimer formed by SPOP and SPOPL are less efficient than ubiquitin ligase complexes containing only SPOP. May function to down-regulate the activity of cullin-RING-based BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complexes that contain SPOP

The "SPOPL Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about SPOPL comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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