SPRR1A: A Potential Drug Target and Biomarker (G6698)

Target Name: SPRR1A

NCBI ID: G6698

SPRR1A

SPRR1A: A Potential Drug Target and Biomarker

SPRR1A, short for Spermidine-Protein Research Revolution 1A, is a gene that encodes a protein known as SPRR1A. The protein is of interest because it has been shown to play a role in a variety of biological processes, including DNA replication, gene expression, and cellular signaling. As a result, SPRR1A has potential as a drug target or biomarker.

SPRR1A functions as a protein that can bind to specific DNA sequences and regulate the activity of the DNA replication machinery. This protein has been shown to be involved in the regulation of gene expression and has been linked to a variety of diseases, including cancer.

One of the key challenges in studying SPRR1A is its high level of homogeneity. While it is found in all eukaryotic cells, it is expressed at different levels in each cell type, which can make it difficult to study. However, researchers have been able to use techniques such as RNA interference and CRISPR/Cas9 to manipulate its expression and study its function.

In addition to its role in DNA replication, SPRR1A has also been shown to play a role in cellular signaling. This protein has been shown to interact with a variety of protein partners, including the protein known as p53, which is a well-known tumor suppressor protein. SPRR1A has also been shown to play a role in the regulation of cellular signaling pathways, including the PI3K/Akt signaling pathway.

SPRR1A's potential as a drug target is based on its involvement in cellular signaling and its association with a variety of diseases. For example, SPRR1A has been shown to be involved in the regulation of cell division and has been linked to the development of cancer. Additionally, SPRR1A has been shown to play a role in the regulation of the immune response, which is important for fighting off infections and diseases.

In addition to its potential as a drug target, SPRR1A also has potential as a biomarker. This is because it has been shown to be expressed in a variety of biological samples, including cancer tissues, which makes it a potential source of diagnostic information. Additionally, because SPRR1A is highly stable and does not have a natural mechanism for degradation, it has the potential to be used as a long-term stable biomarker.

Overall, SPRR1A is a protein that has significant potential as a drug target or biomarker. Its role in DNA replication, cellular signaling, and the regulation of cell division, immune response and inflammation make it an attractive target for drug development. Further studies are needed to fully understand its function and its potential as a drug and biomarker.

Protein Name: Small Proline Rich Protein 1A

Functions: Cross-linked envelope protein of keratinocytes. It is a keratinocyte protein that first appears in the cell cytosol, but ultimately becomes cross-linked to membrane proteins by transglutaminase. All that results in the formation of an insoluble envelope beneath the plasma membrane

The "SPRR1A Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about SPRR1A comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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