SNORA74B: A Small Nucleolar RNA with Promising Potential as a Drug Target

Target Name: SNORA74B

NCBI ID: G677841

SNORA74B

Other Name(s): Small nucleolar RNA, H/ACA box 74B | U19-2 | small nucleolar RNA, H/ACA box 74B

SNORA74B: A Small Nucleolar RNA with Promising Potential as a Drug Target

Small nucleolar RNA (snRNA) is a class of non-coding RNAs that play critical roles in various cellular processes, including DNA replication, gene expression, and RNA splicing. In eukaryotes, snRNA mainly includes snRNA produced by H/ACA box genes and snRNA transcribed from DNA. Among them, the snRNA produced by the H/ACA box gene has special biological functions in organisms, such as regulating gene expression and participating in RNA splicing. SNORA74B is snRNA produced by the H/ACA box gene No. 74, and its function and mechanism in vivo require further study.

SNORA74B molecular structure

SNORA74B is a snRNA of approximately 240 nucleotides in length, which consists of a 74-nucleotide open reading frame (ORF). In the central region of the ORF, there is a conserved H/ACA box domain, which includes one Glu215 and two Asp216. The interaction between Glu215 and Asp216 is a key feature of the H/ACA box, and they may have an impact on the biological function of SNORA74B.

Functions of SNORA74B

The function and mechanism of SNORA74B in vivo require further study. Some studies have shown that SNORA74B may be involved in biological processes such as RNA splicing. For example, some studies have found that SNORA74B plays a role in the RNA splicing process and is closely related to the activity of RNA splicing enzymes. In addition, SNORA74B may also be involved in the regulation of gene expression. For example, studies have shown that SNORA74B may regulate gene expression by binding to DNA-binding proteins.

Pharmacological significance of SNORA74B

As a new molecule, SNORA74B has great pharmacological significance. First, SNORA74B can be used as a drug target to treat a variety of diseases. For example, some studies have found that SNORA74B is up-regulated in a variety of tumors and is closely related to tumor invasion and metastasis. Therefore, intervention targeting SNORA74B may be a promising tumor treatment strategy.

Secondly, SNORA74B can also be used as a biomarker for drug research. Some studies have shown that the expression level of SNORA74B can be used to evaluate the efficacy and resistance of drugs to tumors. Therefore, SNORA74B can be used as an important drug research indicator and provide a theoretical basis for drug development and selection.

Biological significance of SNORA74B

As a new type of molecule, SNORA74B has important biological significance. First of all, the function and mechanism of SNORA74B in vivo require further study. In-depth study of the structure and function of SNORA74B can provide important theoretical and experimental foundations for related research.

Secondly, as a new molecule, SNORA74B has great pharmacological significance. Through the intervention of SNORA74B, new treatment strategies and biomarkers can be provided for various diseases.

Protein Name: Small Nucleolar RNA, H/ACA Box 74B

The "SNORA74B Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about SNORA74B comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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