SNORD114-1: A Potential Drug Target and Biomarker (G767577)

Target Name: SNORD114-1

NCBI ID: G767577

SNORD114-1

Other Name(s): Small nucleolar RNA, C/D box 114-1 | 14q(II-1) | small nucleolar RNA, C/D box 114-1

SNORD114-1: A Potential Drug Target and Biomarker

Small nucleolar RNA (snRNA) is a class of non-coding RNAs that play a critical role in various cellular processes, including DNA replication, gene expression, and RNA processing. One of the most well-known snRNAs is SNORD114-1, which is located in the C/D box on chromosome 114.

The C/D box is a region of DNA that contains a unique continuous double helix composed of G and C nucleotides. This region is known for its variable length and diverse composition, and it is involved in the regulation of various cellular processes. The SNORD114 -1 gene is located within this region and is responsible for the production of a unique snRNA molecule.

SNORD114-1 has been shown to play a critical role in the regulation of gene expression in various organisms. It has been shown to interact with other snRNAs, including snRNA-A28, which is a key regulator of gene expression in bacteria. These interactions suggest that SNORD114-1 may be a potential drug target or biomarker.

One of the key features of SNORD114-1 is its expression pattern. It is highly expressed in various tissues and cells, including the brain, heart, and testes. It is also expressed in the cytoplasm of cultured cells, which suggests that it may be involved in the regulation of cellular processes within the cell.

Another potential mechanism by which SNORD114-1 may be involved in cellular processes is its role in the regulation of DNA replication. Research shows that SNORD114-1 is involved in the regulation of DNA replication in various organisms, including bacteria and yeast. This suggests that it may be a potential drug target or biomarker for therapies that target DNA replication disorders.

In addition to its potential role in cellular processes, SNORD114-1 is also a potential drug target or biomarker due to its unique structure and biology. The C/D box is a region of DNA that is highly conserved across different organisms, which suggests that it may be a useful target for small molecules that can modulate its activity. Additionally, the fact that SNORD114-1 is a unique snRNA molecule may make it more vulnerable to drug targeting, as small molecules may be more effective at interacting with specific regions of the molecule.

Overall, SNORD114-1 is a potential drug target or biomarker due to its unique structure and biology. Its expression pattern and role in cellular processes suggest that it may be involved in a variety of cellular processes, making it a promising target for small molecules. Additionally, its unique structure may make it more vulnerable to drug targeting, making it a promising candidate for future studies.

Protein Name: Small Nucleolar RNA, C/D Box 114-1

The "SNORD114-1 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about SNORD114-1 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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