SNORA80E: A Potential Drug Target and Biomarker (G677823)

Target Name: SNORA80E

NCBI ID: G677823

SNORA80E

Other Name(s): Small nucleolar RNA, H/ACA box 80E | SNORA42 | small nucleolar RNA, H/ACA box 80E | ACA42

SNORA80E: A Potential Drug Target and Biomarker

Small nucleolar RNA (snRNA) is a non-coding RNA molecule that plays a critical role in the regulation of gene expression in eukaryotic cells. One of the key functions of snRNA is to interact with the host cell's DNA to ensure the proper translation of RNA into protein. One of the most well-known snRNAs is SNORA80E, which is located in h/ACA box 80E on chromosome 19.

SNORA80E is a 24-nt RNA molecule that contains 19 exons and 5 intron. It is expressed in most tissues and cells of the human body and is involved in the regulation of various cellular processes, including cell growth, apoptosis, and translation of RNA into protein. One of the most significant functions of SNORA80E is its role in the regulation of gene expression, particularly in the regulation of cell apoptosis.

Apoptosis is a natural and essential process in the life of all cells, which is controlled by a complex interplay of genetic and signaling pathways. Apoptosis is regulated by a variety of factors, including the expression of pro-apoptotic and anti-apoptotic genes, the levels of pro-inflammatory cytokines and chemokines, and the availability of resources such as oxygen and nutrients.

SNORA80E is known to play a critical role in the regulation of apoptosis, particularly in the regulation of cell death during programmed cell death (PDD). PDD is a normal and essential part of cell life, and is regulated by a variety of factors, including the expression of pro-apoptotic and anti-apoptotic genes. SNORA80E is known to be involved in the regulation of PDD by promoting the expression of pro-apoptotic genes and inhibiting the expression of anti-apoptotic genes.

One of the most significant functions of SNORA80E is its ability to promote the expression of pro-apoptotic genes. For example, studies have shown that SNORA80E can enhance the expression of genes involved in cell death, such as the Bcl-2 gene. Bcl-2 is a pro-apoptotic gene that has been implicated in the regulation of cell apoptosis, and is known to be regulated by SNORA80E.

Another function of SNORA80E is its ability to inhibit the expression of anti-apoptotic genes. For example, studies have shown that SNORA80E can inhibit the expression of genes involved in cell survival, such as the p53 gene. P53 is an anti-apoptotic gene that is involved in the regulation of cell survival, and is known to be regulated by SNORA80E.

SNORA80E is also involved in the regulation of translation of RNA into protein, which is an essential process in the regulation of cellular processes. Studies have shown that SNORA80E can interact with the host cell's DNA to ensure the proper translation of RNA into protein. This function of SNORA80E is critical for the regulation of cellular processes, including cell growth and apoptosis.

In conclusion, SNORA80E is a well-known snRNA that is involved in the regulation of gene expression, particularly in the regulation of cell apoptosis. Its functions as a drug target or biomarker make it an attractive target for future research, with potential applications in the development of new therapeutic approaches for the treatment of various diseases.

Protein Name: Small Nucleolar RNA, H/ACA Box 80E

The "SNORA80E Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about SNORA80E comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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