SNORD114-12: A Potential Drug Target and Biomarker (G767590)

Target Name: SNORD114-12

NCBI ID: G767590

SNORD114-12

Other Name(s): Small nucleolar RNA, C/D box 114-12 | small nucleolar RNA, C/D box 114-12 | 14q(II-12)

SNORD114-12: A Potential Drug Target and Biomarker

Small nucleolar RNA (snRNA) is a non-coding RNA molecule that plays a critical role in the regulation of gene expression in eukaryotic cells. One of the key functions of snRNA is to help recruit chromatin-remodeling complexes to specific genomic regions, thereby modifying the chromatin landscape and influencing gene accessibility. C/D box 114-12 is a specific snRNA molecule that has been identified as a potential drug target and biomarker.

The C/D box 114-12 is a 24.8 nucleotide long RNA molecule that is located within the CCRN1 gene on chromosome 16. It is characterized by a highly conserved stem-loop region that is known for its role in snRNA function. The stem- loop region is composed of three regions: the A, B, and C regions. The A region is the most conserved and is involved in the formation of a base-pair with the UUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUU UUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUU UUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUU UUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUU UUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUU UUUUUUUUUUUUUUUUUUUUUUUUUUUUU U

The C/D box 114-12 is a well-conserved region that is involved in the formation of a base-pair with the UUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUU UUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUU UUUUUUUUUUU U

The conservation of the C/D box 114-12 region is important for its role in the regulation of gene expression. Many studies have shown that snRNA molecules can interact with chromatin-remodeling complexes to alter chromatin structure and accessibility. 114-12 is known for its ability to form a base-pair with the UUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUU, which is a common base-pair with many snRNA molecules. The conservation of this base molecules. -pair suggests that the C/D box 114-12 may play a critical role in the regulation of gene expression.

In addition to its role in gene regulation, the C/D box 114-12 is also a potential drug target. Many studies have shown that the C/D box 114-12 interacts with various protein molecules, including the protein tyrosine kinase (TK ) and the RNA-protein binding protein (RBP) family. These interactions suggest that the C/D box 114-12 may be a useful target for small molecule inhibitors.

The C/D box 114-12 is also a potential biomarker for certain diseases. Many studies have shown that the expression of the C/D box 114-12 is altered in various diseases, including cancer, neurodegenerative diseases, and metabolic diseases. These changes in expression may be associated with the development of these diseases and could be used as potential biomarkers for diagnosis and treatment.

In conclusion, the C/D box 114-12 is a well-conserved region of snRNA that is involved in the regulation of gene expression and the regulation of chromatin structure. Its conservation and interaction with chromatin-remodeling complexes suggest that it may be a useful target for small molecule inhibitors and biomarkers. Further research is needed to fully understand the role of the C/D box 114-12 in the regulation of gene expression and the development of various diseases.

Protein Name: Small Nucleolar RNA, C/D Box 114-12

The "SNORD114-12 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about SNORD114-12 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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