SNORA71A: A Small Nucleolar RNA with Promising Potential as a Drug Target

Target Name: SNORA71A

NCBI ID: G26777

SNORA71A

Other Name(s): Small nucleolar RNA, H/ACA box 71A | small nucleolar RNA, H/ACA box 71A | U71a | RNU71A

SNORA71A: A Small Nucleolar RNA with Promising Potential as a Drug Target

Small nucleolar RNA (snRNA), also known as microRNA (miRNA), is a class of non-coding RNAs that play a critical role in post-transcriptional gene regulation. Among the various functions of snRNAs, the H/ACA box 71A has garnered significant attention due to its unique structure and the potential it holds as a drug target or biomarker.

The H/ACA box 71A is a conserved region located between the 5' and 3' ends of snRNAs. It is composed of a unique set of amino acids that includes a hexonucleotide loop, a stem-loop, and a tail. This structure is distinct from other snRNA families and has led to the nickname \"snRNAbox 71A.\" The H/ACA box 71A is expressed in most eukaryotic cells and is involved in various cellular processes, including DNA replication, transcription, and translation.

Recent studies have suggested that H/ACA box 71A may have potential as a drug target or biomarker. One reason for this is the high homology between the H/ACA box 71A and various drug targets, including proteins involved in cell signaling pathways. For instance , the H/ACA box 71A is similar in sequence to the protein known as NF-Y6, which is a key regulator of cell proliferation and growth. Similarly, it is structurally similar to the nuclear protein called MIF, which plays a role in immune responses and inflammation.

Another potential reason why H/ACA box 71A may be a drug target is its involvement in cellular processes that are often disrupted in diseases, such as cancer and neurodegenerative disorders. For example, altered levels of H/ACA box 71A have been observed in various types of cancer, which may indicate a potential role for these diseases in the regulation of nuclear processes. Additionally, H/ACA box 71A has been implicated in the regulation of neurodegenerative disorders, including Alzheimer's disease and Parkinson's disease.

Furthermore, the unique structure of H/ACA box 71A has also led to the possibility of using it as a biomarker for certain diseases. One of the challenges in the diagnosis of certain diseases is the lack of specific and sensitive biomarkers that can aid in their diagnosis. H/ACA box 71A may provide such a biomarker, as its expression levels can be manipulated and detected under various conditions. This may enable the development of diagnostic tests that can accurately diagnose diseases that are currently difficult to diagnose.

In conclusion, H/ACA box 71A is a small nucleolar RNA that has significant potential as a drug target or biomarker. Its unique structure and the conservation of its sequence in different organisms make it an attractive candidate for further investigation. Further studies are needed to determine the functional role of H/ACA box 71A in various cellular processes and its potential as a drug or biomarker.

Protein Name: Small Nucleolar RNA, H/ACA Box 71A

The "SNORA71A Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about SNORA71A comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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